Department of Mechanical Engineering, The University of British Columbia, Vancouver, BC, Canada.
Orthopaedic and Injury Biomechanics Group, ICORD, Vancouver, BC, Canada.
Ann Biomed Eng. 2023 Nov;51(11):2544-2553. doi: 10.1007/s10439-023-03294-y. Epub 2023 Jun 26.
Porcine models in injury biomechanics research often involve measuring head or brain kinematics. Translation of data from porcine models to other biomechanical models requires geometric and inertial properties of the pig head and brain, and a translationally relevant anatomical coordinate system (ACS). In this study, the head and brain mass, center of mass (CoM), and mass moments of inertia (MoI) were characterized, and an ACS was proposed for the pre-adolescent domestic pig. Density-calibrated computed tomography scans were obtained for the heads of eleven Large White × Landrace pigs (18-48 kg) and were segmented. An ACS with a porcine-equivalent Frankfort plane was defined using externally palpable landmarks (right/left frontal process of the zygomatic bone and zygomatic process of the frontal bone). The head and brain constituted 7.80 ± 0.79% and 0.33 ± 0.08% of the body mass, respectively. The head and brain CoMs were primarily ventral and caudal to the ACS origin, respectively. The mean head and brain principal MoI (in the ACS with origin at respective CoM) ranged from 61.7 to 109.7 kg cm, and 0.2 to 0.6 kg cm, respectively. These data may aid the comparison of head and brain kinematics/kinetics data and the translation between porcine and human injury models.
猪模型在损伤生物力学研究中常涉及测量头部或大脑运动学。将猪模型的数据转化到其他生物力学模型中需要猪头部和大脑的几何和惯性特性，以及一个与平移相关的解剖学坐标系（ACS）。本研究对未成年家猪的头部和大脑质量、质心（CoM）和质量惯性矩（MoI）进行了特征描述，并提出了一个 ACS。对 11 头大白×长白猪（18-48 公斤）的头部进行了密度校准的计算机断层扫描，并进行了分割。使用可触及的外部解剖标志（左右颧骨额突和额骨颧骨突）定义了一个具有猪等效法兰克福平面的 ACS。头部和大脑分别占体重的 7.80±0.79%和 0.33±0.08%。头部和大脑的 CoM 主要位于 ACS 原点的腹侧和尾侧。头部和大脑的主要 MoI（在各自 CoM 的 ACS 中）范围为 61.7 至 109.7 kg·cm，分别为 0.2 至 0.6 kg·cm。这些数据可能有助于比较头部和大脑运动学/动力学数据，并在猪和人类损伤模型之间进行转换。
