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狒狒(狒狒属)的骨肉瘤

Osteosarcoma in Baboons (Papio spp).

作者信息

Mezzles Marguerite J, Dick Edward J, Owston Michael A, Bauer Cassondra

机构信息

Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, USA; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.

Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, USA.

出版信息

Comp Med. 2015 Apr;65(2):144-9.

Abstract

Bone neoplasms in baboons (Papio spp) are rare, with only one confirmed case of osteosarcoma previously described in the literature. Over a 12-y period, 6 baboons at a national primate research center presented with naturally occurring osteosarcoma; 3 lesions affected the appendicular skeleton, and the remaining 3 were in the head (skull and mandible). The 6 cases presented were identified in members of a large outdoor-housed breeding colony. The subjects were not genetically related or exposed to the same research conditions. Diagnoses were made based on the presentation and radiographic findings, with histologic confirmation.

摘要

狒狒(狒狒属)的骨肿瘤很罕见,文献中此前仅描述过一例确诊的骨肉瘤病例。在12年的时间里,一家国家灵长类动物研究中心有6只狒狒出现了自然发生的骨肉瘤;3处病变累及四肢骨骼,其余3处位于头部(颅骨和下颌骨)。所呈现的这6例病例是在一个大型户外饲养繁殖群体的成员中发现的。这些受试动物没有亲缘关系,也没有暴露于相同的研究条件下。诊断基于临床表现和影像学检查结果,并经组织学证实。

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本文引用的文献

5
Natural pathology of the Baboon (Papio spp.).狒狒(狒狒属)的自然病理学。
J Med Primatol. 2011 Apr;40(2):142-55. doi: 10.1111/j.1600-0684.2010.00463.x. Epub 2011 Jan 13.
6
Spontaneous neoplasia in the baboon (Papio spp.).狒狒(狒狒属)的自发性肿瘤形成。
J Med Primatol. 2007 Apr;36(2):61-79. doi: 10.1111/j.1600-0684.2006.00202.x.
8
Premalignant conditions of bone.骨的癌前病变
J Orthop Sci. 2006 Jul;11(4):412-23. doi: 10.1007/s00776-006-1037-6.
10
Osteosarcoma: anatomic and histologic variants.骨肉瘤:解剖学和组织学变异型
Am J Clin Pathol. 2006 Apr;125(4):555-81. doi: 10.1309/UC6K-QHLD-9LV2-KENN.

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