Bahamondes Luis, Ali Moazzam
Human Reproduction Unit, Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Campinas Caixa Postal 6181; 13084-971, Campinas Brazil.
Reproductive Health and Research, World Health Organization Avenue Appia CH-1211 Geneva 27 Switzerland.
F1000Prime Rep. 2015 Mar 3;7:33. doi: 10.12703/P7-33. eCollection 2015.
Menstrual disorders are a major reason for gynaecological consultations worldwide and, unfortunately there are many different definitions and classifications of this condition. Clear definitions and terminology are necessary for scientific literature, particularly for clinicians, and for clinical trials comparing two treatments. The International Federation of Gynaecology and Obstetrics (FIGO) Menstrual Disorders Working Group has proposed abandoning the use of one common term, dysfunctional uterine bleeding (DUB), while continuing to use the terms abnormal uterine bleeding (AUB) and heavy menstrual bleeding (HMB). Furthermore, the group issued the PALM-COEIN classification system for menstrual disorders, which has quickly been adopted around the world. The PALM-COEIN system allows clinicians and researchers to identify and classify women with both AUB and HMB in a systematic manner, provides reliable information for research purposes and for epidemiological and prevalence studies in different settings, and supports accurate diagnoses and treatment. Additionally, this classification system is useful for selecting treatments appropriate for different stages of women's reproductive years and for different patterns of menstrual bleeding. Among the proposed treatments are the use of combined oral contraceptives, the levonorgestrel-releasing intrauterine system, tranexamic acid, mefenamic acid, and other nonsteroidal anti-inflammatory drugs (NSAIDs).
月经紊乱是全球范围内妇科门诊的主要原因,不幸的是,对于这种病症有许多不同的定义和分类。清晰的定义和术语对于科学文献来说是必要的,尤其是对于临床医生以及比较两种治疗方法的临床试验而言。国际妇产科联合会(FIGO)月经紊乱工作组提议摒弃一个常用术语——功能失调性子宫出血(DUB),同时继续使用异常子宫出血(AUB)和月经过多(HMB)这两个术语。此外,该小组发布了月经紊乱的PALM-COEIN分类系统,该系统已在全球迅速得到采用。PALM-COEIN系统使临床医生和研究人员能够以系统的方式识别和分类患有AUB和HMB的女性,为研究目的以及不同环境下的流行病学和患病率研究提供可靠信息,并支持准确的诊断和治疗。此外,这种分类系统有助于选择适合女性生殖年限不同阶段以及不同月经出血模式的治疗方法。提议的治疗方法包括使用复方口服避孕药、左炔诺孕酮宫内节育系统、氨甲环酸、甲芬那酸以及其他非甾体抗炎药(NSAIDs)。