Moyo Mack, Aremu Adeyemi O, Van Staden Johannes
Research Centre for Plant Growth and Development, School of Life Sciences, University of KwaZulu-Natal, Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa.
Research Centre for Plant Growth and Development, School of Life Sciences, University of KwaZulu-Natal, Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa.
J Ethnopharmacol. 2015 Nov 4;174:595-606. doi: 10.1016/j.jep.2015.04.034. Epub 2015 Apr 27.
The use of plant species for different therapeutic/medicinal purposes is well-entrenched in sub-Saharan Africa.
To provide a critical and updated review of the enormous medicinal plant heritage in sub-Saharan Africa with regards to the abundance, importance, conservation status and potential means to help sustain their availability for future generations.
A comprehensive literature search involving different online databases, books and theses were conducted in order to obtain, collate and synthesize available information on various fundamental aspects pertaining to African medicinal plants.
African biodiversity hotspots are endowed with a high level of endemic species with a significant portion possessing medicinal value. Apart from the extensive ethnobotanical uses of medicinal plants found in Africa, scientific validation of their biological potential such as antimicrobial, antioxidant, anti-inflammatory and anti-diabetic properties have been recognized. Together with the demand arising from their biological efficacies, other anthropogenic factors are exerting conservation strains of the wild population of these medicinal plants. Even though researchers have acknowledged the importance and value of conserving these medicinal plants, several challenges have hampered these efforts on the Continent as a whole.
The rich flora occurring in sub-Saharan Africa suggests enormous potential for discovery of new chemical entity with therapeutic value. However, concerted efforts focused on documenting the conservation status of African medicinal plants are pertinent. Application of different biotechnological techniques is needed to sustain these valuable botanical entities, especially to meet increasing pharmaceutical demand. Most importantly, increased public enlightenment and awareness may help eradicate the prejudice against cultivation of medicinal plants.
在撒哈拉以南非洲地区,利用植物物种实现不同治疗/药用目的的做法由来已久。
对撒哈拉以南非洲丰富的药用植物遗产进行批判性的最新综述,涉及这些植物的数量、重要性、保护状况以及有助于为子孙后代维持其可得性的潜在方法。
进行了全面的文献检索,涵盖不同的在线数据库、书籍和论文,以获取、整理和综合关于非洲药用植物各个基本方面的现有信息。
非洲生物多样性热点地区拥有大量特有物种,其中很大一部分具有药用价值。除了非洲发现的药用植物广泛的民族植物学用途外,它们的生物潜力,如抗菌、抗氧化、抗炎和抗糖尿病特性,也得到了科学验证。除了因其生物功效产生的需求外,其他人为因素也给这些药用植物的野生种群带来了保护压力。尽管研究人员已经认识到保护这些药用植物的重要性和价值,但整个非洲大陆的这些努力仍受到一些挑战的阻碍。
撒哈拉以南非洲丰富的植物群表明,发现具有治疗价值的新化学实体具有巨大潜力。然而,集中精力记录非洲药用植物的保护状况至关重要。需要应用不同的生物技术来维持这些珍贵的植物实体,特别是为了满足不断增长的制药需求。最重要的是,加强公众宣传和提高认识可能有助于消除对药用植物种植的偏见。