Chen Mei-Jung, Huang Shiau-Shian, Juang Kai-Dih, Chan Chin-Hong
From the Department of Psychiatry, Taichung Veterans General Hospital (M-JC, K-DJ, C-HC); Master of Psychology, Kaohsiung Medical University (M-JC); Department of Psychiatry, Chiayi Branch, Taichung Veterans General Hospital (S-SH); School of Medicine, Chung Shan Medical University (S-SH); Faculty of Medicine, National Yang Ming University (S-SH, K-DJ); Candidate of Master of Epidemics, National Taiwan University, Taiwan, ROC (S-SH); Master of Arts, University of Chicago, Illinois, USA (K-DJ); National Defense Medical Center, Taiwan, ROC (C-HC); Master of Administrative Medicine, University of Wisconsin, Wisconsin, USA (C-HC).
Medicine (Baltimore). 2015 May;94(17):e769. doi: 10.1097/MD.0000000000000769.
Although catatonia is a well defined syndrome, the treatment of chronic catatonia remains an unresolved issue. Here, we report a successful treatment of a 30-year-old patient with treatment-resistant catatonic schizophrenia in 10 years by augmentation of selective serotonin reuptake inhibitors (SSRIs).We present a 30-year-old man with treatment-resistant catatonic schizophrenia who failed to respond to the treatment of benzodiazepines and antipsychotics for 10 years. He markedly improved after taking SSRIs. Now, he does not hold odd postures and begins to talk and show more facial expressions.We postulate that the therapeutic effect is related to the enhancement of 5-HT neurotransmission. SSRIs can be a considerable choice to treat chronic catatonia.
尽管紧张症是一种定义明确的综合征，但慢性紧张症的治疗仍是一个未解决的问题。在此，我们报告了一例30岁难治性紧张型精神分裂症患者，通过增加选择性5-羟色胺再摄取抑制剂（SSRI）治疗，在10年中获得成功治愈。我们介绍了一名30岁患有难治性紧张型精神分裂症的男性，他对苯二氮䓬类药物和抗精神病药物治疗10年无效。服用SSRI后他有显著改善。现在，他不再保持怪异姿势，开始说话并展现出更多面部表情。我们推测治疗效果与5-羟色胺神经传递增强有关。SSRI可以作为治疗慢性紧张症的一个重要选择。
