Yoldaş Tayfun, Erol Varlık, Çalışkan Cemil, Akgün Erhan, Korkut Mustafa
Department of General Surgery, Ege University Faculty of Medicine, İzmir, Turkey.
Ulus Cerrahi Derg. 2013 Jun 1;29(2):72-5. doi: 10.5152/UCD.2013.41. eCollection 2013.
Spontaneous intestinal intramural hematoma is a rare complication of anticoagulant treatment. In this study, we retrospectively evaluated 14 patients with the diagnosis of intramural hematoma of the small intestine who were followed-up and treated in our clinic, and we aimed to determine current approaches in the diagnosis and treatment of intramural hematoma.
Between February 2010-October 2012, 14 patients diagnosed with small intestinal intramural hematoma were retrospectively analyzed. Nine patients were followed due to clinical findings and 5 patients underwent operation with a histopathological diagnosis of intramural hematoma.
Abdominal computed tomography demonstrated ileal and jejunal wall thickening in 10 patients, while findings were consistent with mesenteric vascular disease in four. Five patients were operated due to mechanical bowel obstruction and acute abdomen. The other 9 patients were followed up with medical treatment and 8 of these patients were already using warfarin due to cardiac bypass and valve replacement.
Spontaneous intestinal intramural hematoma is a rare cause of small bowel obstruction due to intramural hematoma, which is encountered even more rarely. An intramural hematoma should be considered among differential diagnosis of patients who present with abdominal pain and symptoms of obstruction with a history of anticoagulant drug use and elevated International Normalized Ratio (INR) levels. Early diagnosis and medical follow-up can provide a good response to treatment in the majority of patients without requiring surgery.
自发性肠壁内血肿是抗凝治疗的一种罕见并发症。在本研究中,我们回顾性评估了在我院接受随访和治疗的14例诊断为小肠壁内血肿的患者,旨在确定目前壁内血肿的诊断和治疗方法。
对2010年2月至2012年10月期间诊断为小肠壁内血肿的14例患者进行回顾性分析。9例因临床表现进行随访,5例接受手术,组织病理学诊断为壁内血肿。
腹部计算机断层扫描显示10例患者回肠和空肠壁增厚,4例患者的表现与肠系膜血管疾病一致。5例因机械性肠梗阻和急腹症接受手术。其他9例患者接受药物治疗随访,其中8例因心脏搭桥和瓣膜置换已在使用华法林。
自发性肠壁内血肿是壁内血肿导致小肠梗阻的罕见原因,这种情况更为罕见。对于有腹痛和梗阻症状且有抗凝药物使用史和国际标准化比值(INR)水平升高的患者,鉴别诊断时应考虑壁内血肿。早期诊断和药物随访可使大多数患者无需手术即可获得良好的治疗反应。