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贝利尤单抗对活动性系统性红斑狼疮患者疗效的真实生活经验。

Real life experience on the effect of Belimumab in patients with active systemic lupus.

作者信息

Scheinberg Morton, Golmia Ricardo

机构信息

Clinical Research Center Hospital AACD, São Paulo, 04032-060 Brazil.

出版信息

Springerplus. 2014 Dec 22;3:758. doi: 10.1186/2193-1801-3-758. eCollection 2014.

Abstract

INTRODUCTION

To evaluate real life experience on the effect of Belimumab in patients with active systemic lupus erythematosus.

CASE PRESENTATION

Twenty patinets with musclesketal symptoms were evaluated, three were discontinued for different resons and seventeen completed eight injections of Belimumab during a six month period. A fatigue score was also evaluated at the same time.

DISCUSSION AND EVALUATION

Marked reduction of disease activity and fatigue score were observed in the patient group.

CONCLUSIONS

Belimumab is a novel form of therapy in patients with active systemic lupus erythematosus to be added in the standard of care particularly in patients with skin and joint symptoms.

摘要

引言

评估贝利尤单抗对活动性系统性红斑狼疮患者疗效的实际生活经验。

病例介绍

对20例有肌肉骨骼症状的患者进行了评估,3例因不同原因停药,17例在6个月期间完成了8次贝利尤单抗注射。同时还评估了疲劳评分。

讨论与评估

在患者组中观察到疾病活动度和疲劳评分显著降低。

结论

贝利尤单抗是活动性系统性红斑狼疮患者的一种新型治疗方法,应添加到护理标准中,特别是对有皮肤和关节症状的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af37/4409606/9af8b338d2da/40064_2014_1511_Fig1_HTML.jpg

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