Hawker G, Gabriel S, Bombardier C, Goldsmith C, Caron D, Gladman D
Department of Medicine, Wellesley Hospital, Toronto, ON, Canada.
J Rheumatol. 1993 Apr;20(4):657-60.
SLEDAI, a disease activity index for systemic lupus erythematosus (SLE) has been validated against other such indices and its reliability has been shown by specialists in SLE. To assess its reliability among less experienced clinicians, we conducted a reliability study with 3 rheumatology trainees and 9 patients with SLE according to a Latin square design. SLEDAI easily distinguished between patients (p = 0.0009), and physician variability was not statistically significant (p = 0.27). Inter and intraobserver agreement were 78.7 and 98.0%, respectively. SLEDAI was thus shown to be a reliable instrument among less experienced observers for the assessment of disease activity in SLE.
系统性红斑狼疮疾病活动指数（SLEDAI）已与其他此类指数进行了验证，并且系统性红斑狼疮专家已证明其可靠性。为了评估其在经验不足的临床医生中的可靠性，我们根据拉丁方设计对3名风湿病实习医生和9名系统性红斑狼疮患者进行了一项可靠性研究。SLEDAI能够轻松区分患者（p = 0.0009），并且医生之间的差异无统计学意义（p = 0.27）。观察者间和观察者内的一致性分别为78.7%和98.0%。因此，SLEDAI被证明是经验不足的观察者评估系统性红斑狼疮疾病活动的可靠工具。
