脉络膜厚度与体重指数的相关性

CORRELATION OF CHOROIDAL THICKNESS AND BODY MASS INDEX.

作者信息

Yilmaz Ihsan, Ozkaya Abdullah, Kocamaz Murat, Ahmet Sibel, Ozkaya Hande M, Yasa Dilek, Agca Alper, Yazici Ahmet T, Demirok Ahmet

机构信息

*Beyoglu Eye Training and Research Hospital, Istanbul, Turkey; †Department of Endocrinology and Metabolism, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey; and ‡Department of Ophthalmology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.

出版信息

Retina. 2015 Oct;35(10):2085-90. doi: 10.1097/IAE.0000000000000582.

DOI:10.1097/IAE.0000000000000582

PMID:25932552

Abstract

PURPOSE

To evaluate the possible changes in the microvascular structure of the choroid by measuring choroidal thickness (CT) in four different body mass index (BMI) groups of healthy individuals.

METHODS

One hundred and sixty eyes of 160 healthy individuals (70 females and 90 males) were included in this cross-sectional study. Healthy individuals were divided into 4 groups according to their BMIs. Cases with BMI ≤ 18.50 formed Group 1, cases with BMI between 18.50 and 24.99 formed Group 2, cases with BMI between 25.00 and 29.99 formed Group 3, and cases with BMI between 30.00 and 34.99 formed Group 4. The CT was measured by the enhanced depth imaging technique of the spectral domain optical coherence tomography. The CT was measured at subfoveal area and at 500-μm intervals to the nasal and temporal to the fovea up to 2,000 μm. The measurements were then statistically compared among the four groups.

RESULTS

The mean ages were 26.5 ± 6.9 years (range: 18-39 years) in Group 1, 27.2 ± 5.0 (range: 21-38 years) in Group 2, 28.5 ± 5.9 (range: 20-40 years) in Group 3, and 29.25 ± 5.6 (range: 20-40 years) in Group 4. The mean subfoveal CT (in micrometers) was 378 ± 86 (range: 189-563) in Group 1, 384 ± 102 (range: 225-643) in Group 2, 314 ± 66 (range: 160-455) in Group 3, and 317 ± 63 (range: 220-411) in Group 4. There was a statistically significant difference among the 4 groups in regard to CT in all locations (P < 0.05).

CONCLUSION

We have demonstrated that BMI may have an influence on the CT of healthy persons. Individuals in both Group 3 and Group 4 have thinner choroids than the individuals in both Group 1 and Group 2.

摘要

目的

通过测量健康个体四个不同体重指数（BMI）组的脉络膜厚度（CT），评估脉络膜微血管结构的可能变化。

方法

本横断面研究纳入了160名健康个体的160只眼睛（70名女性和90名男性）。健康个体根据其BMI分为4组。BMI≤18.50的病例形成第1组，BMI在18.50至24.99之间的病例形成第2组，BMI在25.00至29.99之间的病例形成第3组，BMI在30.00至34.99之间的病例形成第4组。采用光谱域光学相干断层扫描的增强深度成像技术测量CT。在黄斑中心凹下区域以及从黄斑中心凹向鼻侧和颞侧每隔500μm直至2000μm处测量CT。然后对四组之间的测量结果进行统计学比较。

结果

第1组的平均年龄为26.5±6.9岁（范围：18 - 39岁），第2组为27.2±5.0（范围：21 - 38岁），第3组为28.5±5.9（范围：20 - 40岁），第4组为29.25±5.6（范围：20 - 40岁）。第1组黄斑中心凹下平均CT（单位：微米）为378±86（范围：189 - 563），第2组为384±102（范围：225 - 643），第3组为314±66（范围：160 - 455），第4组为317±63（范围：220 - 411）。在所有测量位置，四组之间的CT存在统计学显著差异（P < 0.05）。