Suppr超能文献

术前营养不良作为中国老年髋关节手术患者术后死亡的独立危险因素:一项单中心观察性研究。

Preoperative malnutrition as an independent risk factor for the postoperative mortality in elderly Chinese individuals undergoing hip surgery: a single-center observational study.

作者信息

Feng Long, Chen Wenji, Ping Ping, Ma Tao, Li Yang, Xu Longhe, Feng Zeguo, Zhao Yali, Fu Shihui

机构信息

Department of Anesthesiology, Hainan Hospital of Chinese People's Liberation Army General Hospital, Sanya, China.

Department of Rheumatology, Hainan Hospital of Chinese People's Liberation Army General Hospital, Sanya, China.

出版信息

Ther Adv Chronic Dis. 2022 Jun 27;13:20406223221102739. doi: 10.1177/20406223221102739. eCollection 2022.

Abstract

OBJECTIVE

Malnutrition is prevalent in elderly with hip fracture and higher than in community-dwelling older adults. Scarce studies have examined the association between preoperative malnutrition and postoperative mortality in elderly Chinese individuals with hip fracture. This study was designed to explore the effect of preoperative malnutrition on the postoperative long-term mortality in elderly Chinese individuals undergoing hip surgery.

METHODS

As a single-center observational study, this study included 263 consecutive patients above 70 years old with hip fracture and elective surgery. Preoperative nutritional status was evaluated by prognostic nutritional index (PNI). Patients were divided into one group with malnutrition (26 patients with PNI ⩽ 38) and the other group without malnutrition (169 patients with PNI > 38), respectively.

RESULTS

The overall malnutrition rate was 13.3% (26 patients). The postoperative long-term mortality rates of patients with and without malnutrition had statistically significant difference [10 patients (38.5%) and 32 patients (18.9%),  < 0.05]. Cox regression analysis showed that malnutrition (hazard ratio: 0.269, 95% confidence interval: 0.085-0.859,  < 0.05) and partial pressure of carbon dioxide (hazard ratio: 0.873, 95% confidence interval: 0.790-0.964,  < 0.05) were independent risk factors for the postoperative long-term mortality.

CONCLUSION

This study demonstrated that preoperative malnutrition was an independent risk factor for the postoperative long-term mortality and resulted in a more than 2.5-fold increase of the postoperative long-term mortality in elderly Chinese individuals undergoing hip surgery.

摘要

目的

营养不良在髋部骨折的老年人中普遍存在,且高于社区居住的老年人。针对中国老年髋部骨折患者术前营养不良与术后死亡率之间的关联,相关研究较少。本研究旨在探讨术前营养不良对接受髋关节手术的中国老年患者术后长期死亡率的影响。

方法

作为一项单中心观察性研究,本研究纳入了263例连续的70岁以上髋部骨折且接受择期手术的患者。术前营养状况通过预后营养指数(PNI)进行评估。患者分别被分为营养不良组(26例PNI≤38)和非营养不良组(169例PNI>38)。

结果

总体营养不良率为13.3%(26例患者)。营养不良组和非营养不良组患者的术后长期死亡率有统计学显著差异[10例患者(38.5%)和32例患者(18.9%),P<0.05]。Cox回归分析显示,营养不良(风险比:0.269,95%置信区间:0.085-0.859,P<0.05)和二氧化碳分压(风险比:0.873,95%置信区间:0.790-0.964,P<0.05)是术后长期死亡率的独立危险因素。

结论

本研究表明,术前营养不良是术后长期死亡率的独立危险因素,导致接受髋关节手术的中国老年患者术后长期死亡率增加超过2.5倍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0300/9243382/61192fc76a42/10.1177_20406223221102739-fig1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验