Lisachenko G V, Evtushenko A Ia
Kardiologiia. 1989 Sep;29(9):87-9.
Cardiac output and parameters of myocardial contractility in the post-resuscitation++ period of acute coronarogenic infarction were studied in experiments on dogs anesthetized with nembutal (40 mg/kg) (29 dogs). Twelve dogs reanimated after fibrillation-induced cardiac arrest were used as controls. The duration of clinical death was 5 minutes. The experimental animals showed a phase pattern of changes with initial hyperperfusion that was less pronounced in infarction and with subsequent one that was more profound than did the controls. A greater degree of +blood circulation disturbances were shown to be associated with high postresuscitation death rates. Diminished cardiac output is originally related to inhibited myocardial contractility; subsequently, of great importance are hypovolemia and arrhythmias.
在以戊巴比妥(40毫克/千克)麻醉的犬类(29只犬)实验中,研究了急性冠状动脉性梗死复苏后期的心输出量和心肌收缩性参数。12只在诱导室颤致心脏骤停后复苏的犬用作对照。临床死亡持续时间为5分钟。实验动物呈现出一种变化的阶段性模式,起初是灌注过多,在梗死情况中不太明显,随后的灌注过多则比对照犬更为显著。更大程度的血液循环紊乱与复苏后高死亡率相关。心输出量减少最初与心肌收缩性受抑制有关;随后,低血容量和心律失常变得极为重要。