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高左心室流出道梯度:主动脉瓣狭窄、梗阻性肥厚型心肌病还是两者皆有?

High left ventricular outflow tract gradient: Aortic stenosis, obstructive hypertrophic cardiomyopathy or both?

作者信息

Almeida Inês, Caetano Francisca, Trigo Joana, Mota Paula, Marques António Leitão

机构信息

Serviço de Cardiologia, Centro Hospitalar e Universitário de Coimbra - Hospital Geral, Coimbra, Portugal.

Serviço de Cardiologia, Centro Hospitalar e Universitário de Coimbra - Hospital Geral, Coimbra, Portugal.

出版信息

Rev Port Cardiol. 2015 May;34(5):357.e1-5. doi: 10.1016/j.repc.2014.10.007. Epub 2015 Apr 29.

DOI:10.1016/j.repc.2014.10.007
PMID:25935071
Abstract

The authors report the case of a patient diagnosed with both hypertrophic cardiomyopathy and aortic stenosis. Due to clinical deterioration, additional investigation was performed, and a high left ventricular outflow tract gradient was identified. Correct identification of the condition causing the symptoms was challenging, and involved several imaging techniques, the contribution of transesophageal echocardiography being crucial. The final diagnosis of severe aortic stenosis led to successful valve replacement surgery. The presence of these two conditions in the same patient has been documented, although it is uncommon. This association poses particular diagnostic and therapeutic challenges, which are discussed in this paper.

摘要

作者报告了一例同时被诊断为肥厚型心肌病和主动脉瓣狭窄的患者病例。由于临床病情恶化,进行了进一步检查,发现左心室流出道压力阶差较高。准确识别导致症状的病情具有挑战性,涉及多种成像技术,其中经食管超声心动图的作用至关重要。最终诊断为重度主动脉瓣狭窄,随后成功进行了瓣膜置换手术。同一患者身上存在这两种病症的情况已有记录,尽管并不常见。本文讨论了这种关联所带来的特殊诊断和治疗挑战。

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Comput Biol Med. 2022 Jul;146:105613. doi: 10.1016/j.compbiomed.2022.105613. Epub 2022 May 15.
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Discrete Subaortic Stenosis: Perspective Roadmap to a Complex Disease.离散性主动脉瓣下狭窄:复杂疾病的前景路线图
Front Cardiovasc Med. 2018 Sep 13;5:122. doi: 10.3389/fcvm.2018.00122. eCollection 2018.
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Evaluation and Management of Concomitant Hypertrophic Obstructive Cardiomyopathy and Valvular Aortic Stenosis.
肥厚性梗阻性心肌病合并主动脉瓣狭窄的评估与管理
Curr Treat Options Cardiovasc Med. 2016 Mar;18(3):17. doi: 10.1007/s11936-016-0440-3.