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对危地马拉一个玛雅原住民群体中的16个常染色体短串联重复序列和17个Y染色体短串联重复序列进行分析。

Analysis of 16 autosomal STRs and 17 Y-STRs in an indigenous Maya population from Guatemala.

作者信息

Cardoso Sergio, Sevillano Rubén, Illescas María J, de Pancorbo Marian Martínez

机构信息

BIOMICs Research Group, Centro de Investigación "Lascaray" Ikergunea, Universidad del País Vasco UPV/EHU, Vitoria-Gasteiz, Spain.

Departamento de la Administración de Justicia, Servicio de Patología-Gipuzkoa-del IVML (Instituto Vasco de Medicina Legal), Gobierno Vasco, Spain.

出版信息

Int J Legal Med. 2016 Mar;130(2):365-6. doi: 10.1007/s00414-015-1195-1. Epub 2015 May 3.

Abstract

The aim of this study was to contribute new data on autosomal STR and Y-STR markers of the Mayas from Guatemala in order to improve available databases of forensic interest. We analyzed 16 autosomal STR markers in a population sample of 155 indigenous Maya and 17 Y-chromosomal STR markers in the 100 males of the sample. Deviations from Hardy-Weinberg equilibrium and linkage disequilibrium between autosomal STR markers were not observed at any loci. The combined power of exclusion was estimated as 99.9991% and the combined power of discrimination was >99.999999999999%. Haplotype diversity of Y-STRs was calculated as 0.9984 ± 0.0018 and analysis of pairwise genetic distances (Rst) supported the Native American background of the population.

摘要

本研究的目的是提供危地马拉玛雅人的常染色体STR和Y-STR标记的新数据,以完善法医相关的现有数据库。我们分析了155名玛雅原住民群体样本中的16个常染色体STR标记,并在样本中的100名男性中分析了17个Y染色体STR标记。在任何位点均未观察到常染色体STR标记偏离哈迪-温伯格平衡和连锁不平衡。排除组合概率估计为99.9991%,鉴别组合概率>99.999999999999%。Y-STR的单倍型多样性计算为0.9984±0.0018,成对遗传距离(Rst)分析支持该群体的美洲原住民背景。

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