Perveen Rukhsana, Shahid Ahmad Ali, Shafique Muhammad, Shahzad Muhammad, Husnain Tayyab
Forensic DNA Typing Laboratory, National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore,, Pakistan.
Forensic Services Laboratory, Centre for Applied Molecular Biology, University of the Punjab, Lahore,, Pakistan.
Int J Legal Med. 2017 Sep;131(5):1239-1240. doi: 10.1007/s00414-017-1544-3. Epub 2017 Jan 30.
This study comprises genetic characterization of 15 autosomal and 17 Y-chromosomal STR loci in 103 unrelated male inhabitants of the Sindhi population to establish its lineage and parameters of forensic interest. The examined autosomal STRs revealed high combined power of discrimination, combined power of exclusion, and the combined matching probability as 0.99999999999999999042580, 0.9999977141, and 9.5742 × 10, respectively. A total of 89 unique haplotypes were obtained, of which 84 were observed once with a haplotype diversity value of 0.999677. The resulted Y-STR haplotypes exhibited a high degree of geographical demarcation by comparing with other populations at the local and global levels.
本研究对103名信德族无关男性居民的15个常染色体和17个Y染色体STR基因座进行了基因特征分析,以确定其谱系和法医鉴定相关参数。所检测的常染色体STR显示出较高的鉴别联合概率、排除联合概率和联合匹配概率,分别为0.99999999999999999042580、0.9999977141和9.5742×10。共获得89种独特单倍型,其中84种仅出现一次,单倍型多样性值为0.999677。通过与本地和全球其他人群比较,所得Y-STR单倍型呈现出高度的地理划分。