Lin Feng, Pu Qiang, Ma Lin, Liu Chengwu, Mei Jiandong, Liao Hu, Xiao Zhilan, Guo Chenglin, Liu Lunxu
Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China Department of Thoracic Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Interact Cardiovasc Thorac Surg. 2015 Aug;21(2):206-10. doi: 10.1093/icvts/ivv112. Epub 2015 May 2.
Primary mediastinal myelolipoma (PMM) is a rare benign tumour composed of haematopoietic tissue and mature adipose tissue. Here, we report the largest series aiming to investigate the outcomes of surgical treatment for patients with PMM.
We retrospectively reviewed the data of 12 patients operated in a single institute during the period between April 2008 and December 2014.
There were 7 female and 5 male patients between 54 and 73 years old (median age, 64 years). Among them, 11 patients underwent unilateral (n = 10) or bilateral (n = 1) mass resection via video-assisted thoracic surgery (VATS), and 1 patient underwent a planned open thoracotomy due to a large tumour volume. The VATS operating time ranged from 20 to 65 min (median, 30 min) and intraoperative blood loss ranged from 20 to 60 ml (median, 30 ml). The open thoracotomy operating time was 120 min, and the blood loss was 1000 ml; thus, the patient received blood transfusion (2 units of RBCs). No operative mortalities or major postoperative complications were observed. All patients experienced a regular follow-up ranging from 2 to 80 months with a median follow-up of 18 months. No recurrence was observed at the time of evaluation.
Surgical treatment is recommended for the diagnosis and treatment of PMM, while VATS is a safe and feasible option in most cases.
原发性纵隔髓脂肪瘤（PMM）是一种由造血组织和成熟脂肪组织组成的罕见良性肿瘤。在此，我们报告了规模最大的系列研究，旨在探讨PMM患者的手术治疗结果。
我们回顾性分析了2008年4月至2014年12月期间在单一机构接受手术的12例患者的数据。
患者共12例，其中女性7例，男性5例，年龄在54至73岁之间（中位年龄64岁）。其中，11例患者通过电视辅助胸腔镜手术（VATS）进行了单侧（n = 10）或双侧（n = 1）肿块切除，1例患者因肿瘤体积较大接受了计划性开胸手术。VATS手术时间为20至65分钟（中位时间30分钟），术中出血量为20至60毫升（中位出血量30毫升）。开胸手术时间为120分钟，出血量为1000毫升；因此，该患者接受了输血（2单位红细胞）。未观察到手术死亡或严重术后并发症。所有患者均接受了2至80个月的定期随访，中位随访时间为18个月。评估时未观察到复发情况。
推荐手术治疗用于PMM的诊断和治疗，而在大多数情况下，VATS是一种安全可行的选择。
