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病例报告:空肠胃肠道间质瘤,一种罕见肿瘤,诊断具有挑战性但治疗成功。

Case Report: Jejunal gastrointestinal stromal tumour, a rare tumour, with a challenging diagnosis and a successful treatment.

作者信息

Sankey Ruth E, Maatouk Mohamed, Mahmood Arshad, Raja Mazhar

机构信息

General Surgery Department, Milton Keynes General Hospital, Milton Keynes, UK

General Surgery Department, Milton Keynes General Hospital, Milton Keynes, UK.

出版信息

J Surg Case Rep. 2015 May 1;2015(5):rjv050. doi: 10.1093/jscr/rjv050.

Abstract

Gastrointestinal stromal tumours (GISTs) are rare. GISTs comprise 0.2% of gastrointestinal tumours and only 0.04% of small intestinal tumours. Jejunal GISTs are the rarest subtype. Only 10-30% progress to malignancy [Choi (Response evaluation of gastrointestinal stromal tumors. Oncologist 2008; 13: :4-7)]. We present a 70-year-old male, with multiple co-morbidities, who had extensive investigations over 5 years for vague abdominal pain. All investigations were normal. He presented with symptoms and signs of small bowel obstruction (SBO), confirmed on a computed tomography scan and demonstrated to be secondary to lesion-induced intussusception. The patient had emergency small bowel resection, was discharged after 4 days and remains well. This case report highlights the rarity of jejunal GISTs and, as extensive initial investigation yielded all false-negative results, indicates the difficulty in diagnosing jejunal GISTs. Adhesions are the commonest cause of SBO in patients with previous abdominal surgery, followed by newly diagnosed malignancies [Beardsley et al. (Small bowel obstruction in the virgin abdomen: the need for a mandatory laparotomy explored. Am J Surg 2014; 208: :243-8)]. Consequently, in patients with a virgin abdomen, underlying tumours should be considered.

摘要

胃肠道间质瘤(GISTs)较为罕见。GISTs占胃肠道肿瘤的0.2%,仅占小肠肿瘤的0.04%。空肠GISTs是最罕见的亚型。只有10% - 30%会进展为恶性肿瘤[Choi(胃肠道间质瘤的疗效评估。肿瘤学家2008年;13: 4 - 7)]。我们报告一例70岁男性,患有多种合并症,因不明原因的腹痛在5年期间接受了广泛检查。所有检查结果均正常。他出现小肠梗阻(SBO)的症状和体征,经计算机断层扫描证实,显示为病变引起的肠套叠所致。患者接受了急诊小肠切除术,4天后出院,目前情况良好。本病例报告强调了空肠GISTs的罕见性,并且由于最初的广泛检查均得出假阴性结果,表明空肠GISTs的诊断存在困难。粘连是既往有腹部手术史患者发生SBO的最常见原因,其次是新诊断的恶性肿瘤[Beardsley等人(未做过腹部手术患者的小肠梗阻:探讨强制剖腹手术的必要性。美国外科杂志2014年;208: 243 - 8)]。因此,对于未做过腹部手术的患者,应考虑潜在肿瘤的可能性。

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