Ssentongo Paddy, Egan Mark, Arkorful Temitope E, Dorvlo Theodore, Scott Oneka, Oh John S, Amponsah-Manu Forster
Center for Neural Engineering, Department of Engineering, Science and Mechanics, Pennsylvania State University, University Park, PA, USA.
Department of Pathology, Eastern Regional Hospital, P.O. Box 201, Koforidua, Ghana.
Case Rep Surg. 2018 Aug 6;2018:1395230. doi: 10.1155/2018/1395230. eCollection 2018.
We present a rare case of gastrogastric intussusception due to gastrointestinal stromal tumor (GIST) and the largest comprehensive literature review of published case reports on gastrointestinal (GI) intussusception due to GIST in the past three decades. We found that the common presenting symptoms were features of gastrointestinal obstruction and melena. We highlight the diagnostic challenges faced in low-resource countries. Our findings emphasize the importance of early clinical diagnosis in low-resource settings in order to guide timely management. In addition, histological analysis of the tumor for macroscopic and microscopic characteristics including mitotic index and c-Kit/CD117 status should be obtained to guide adjuvant therapy with imatinib mesylate. Periodic follow-up to access tumor recurrence is fundamental and should be the standard of care.
我们报告了一例罕见的因胃肠道间质瘤（GIST）导致的胃胃套叠病例，并对过去三十年中已发表的关于GIST导致的胃肠道套叠病例报告进行了最大规模的综合文献综述。我们发现常见的临床表现为胃肠道梗阻和黑便。我们强调了资源匮乏国家所面临的诊断挑战。我们的研究结果强调了在资源匮乏地区进行早期临床诊断以指导及时治疗的重要性。此外，应获取肿瘤的组织学分析，以了解其宏观和微观特征，包括有丝分裂指数和c-Kit/CD117状态，从而指导甲磺酸伊马替尼的辅助治疗。定期随访以监测肿瘤复发至关重要，应成为标准的治疗措施。
