Pfaff Johannes, Herweh Christian, Pham Mirko, Schönenberger Silvia, Bösel Julian, Ringleb Peter A, Heiland Sabine, Bendszus Martin, Möhlenbruch Markus
Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany.
Department of Neurology, University of Heidelberg, Heidelberg, Germany.
J Neurointerv Surg. 2016 Jun;8(6):621-5. doi: 10.1136/neurintsurg-2015-011744. Epub 2015 May 2.
Mechanical thrombectomy (MT) using stent-retrievers has been proven to be a safe and effective treatment in acute ischemic stroke (AIS), particularly in large vessel occlusion. Other than patient characteristics, time to recanalization is the most important factor linked to outcome. MT is usually performed in a dedicated angiography suite using a floor- and/or ceiling-mounted biplane angiographic system. Here we report our first experience of MT with a new combined CT and mobile C-arm X-ray device setup.
Patients with AIS underwent stroke imaging (non-contrast enhanced CT, CT perfusion, and CT angiography) using a commercially available 64-slice CT scanner which was modified for combined use with a C-arm system. In patients with large vessel occlusion, MT was conducted without further patient transfer within the CT imaging suite using a mobile C-arm X-ray device equipped with a 30×30 cm (12×12 inch), 1.5×1.5 k full-view flat detector which was positioned between the gantry and patient table. The safety and feasibility of this new system was assessed in preliminary patients.
Angiographic imaging quality of the mobile C-arm was feasible and satisfactory for diagnostic angiography and MT. Using this setup, time between stroke imaging and groin puncture (picture-to-puncture time) was reduced by up to 35 min (including time for preparation of the patient such as intubation).
MT using a combined CT/C-arm system is safe and feasible. The potential advantages, particularly time saving and ensuing improvement in patient outcome, need to be assessed in a larger study.
使用支架取栓器进行机械取栓已被证明是急性缺血性卒中(AIS),尤其是大血管闭塞的一种安全有效的治疗方法。除患者特征外,再通时间是与预后相关的最重要因素。机械取栓通常在专用血管造影室使用落地式和/或天花板式双平面血管造影系统进行。在此,我们报告首次使用新型CT与移动C形臂X射线设备组合进行机械取栓的经验。
AIS患者使用商用64层CT扫描仪进行卒中成像(非增强CT、CT灌注和CT血管造影),该扫描仪经过改装可与C形臂系统联合使用。对于大血管闭塞的患者,在CT成像室内使用配备30×30 cm(12×12英寸)、1.5×1.5 k全视野平板探测器的移动C形臂X射线设备,无需进一步转运患者即可进行机械取栓,该设备位于机架和检查床之间。在初步纳入的患者中评估了该新系统的安全性和可行性。
移动C形臂的血管造影成像质量对于诊断性血管造影和机械取栓是可行且令人满意的。使用这种设置,卒中成像与腹股沟穿刺之间的时间(图像到穿刺时间)最多可减少35分钟(包括患者准备时间,如插管)。
使用CT/C形臂组合系统进行机械取栓是安全可行的。其潜在优势,尤其是节省时间及随之而来的患者预后改善,需要在更大规模的研究中进行评估。