Narang Pratibha, Mendiratta Deepak K, Tyagi Naresh K, Jajoo Ullhas N, Tayade Atul T, Parihar Pratapsingh H, Narang Rahul, Mishra Pranav S, Anjinappa Sharda M, Chadha Vineet K
Department of Microbiology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India.
Department of Demography & Statistics, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India.
J Epidemiol Glob Health. 2015 Dec;5(4 Suppl 1):S11-8. doi: 10.1016/j.jegh.2015.03.002. Epub 2015 Apr 30.
A house based survey was conducted during 2007-2009 in a representative sample of population in Wardha district implementing Directly Observed Treatment Short Course strategy for tuberculosis (TB) control since 2001. The objective was to estimate prevalence of bacillary pulmonary TB (PTB) in individuals aged 15 years or above, and to estimate trends in prevalence when compared to a previous survey carried out in mid 1980's. Two sputum samples (one spot, one early morning) collected from individuals having symptoms suggestive of PTB, history of previous anti-TB treatment (ATT) or abnormal pulmonary shadow on Mass Miniature Radiography (MMR) consistent with possibly or probably active tuberculosis were subjected to Ziehl-Neelsen microscopy and culture on Lowenstein-Jensen medium. Of 55,096 individuals registered into the survey, 50,332 (91.4%) were screened by interview for symptoms and history of ATT and/or by MMR. Of them, 4805 were eligible for sputum collection; both specimens were collected in 4285 (89.2%) and only one specimen in 27 (0.6%). A total of 86 bacillary cases were detected during the survey. Prevalence of bacillary PTB was estimated at 188.7 (140.3-236.9) per 100,000 populations. There was a decline of 61% in the prevalence of PTB over a period of 22 years.
2007年至2009年期间，在瓦尔道哈区具有代表性的人群样本中开展了一项入户调查。自2001年起，该区就实施了结核病直接督导下的短程治疗策略。目的是估算15岁及以上人群中细菌性肺结核（PTB）的患病率，并与20世纪80年代中期开展的一项前期调查相比，估算患病率的变化趋势。从有PTB症状、既往抗结核治疗史或胸部X线缩影摄片（MMR）显示肺部阴影异常且可能或很可能患有活动性结核病的个体中采集两份痰标本（一份即时痰，一份晨痰），进行萋-尼氏染色显微镜检查并接种于罗-琴培养基上培养。在登记参加此次调查的55096名个体中，50332名（91.4%）接受了访谈，以了解症状、抗结核治疗史和/或进行MMR检查。其中，4805名符合痰标本采集条件；4285名（89.2%）采集了两份标本，27名（0.6%）仅采集了一份标本。此次调查共检测到86例细菌学确诊病例。细菌性PTB的患病率估计为每10万人188.7例（140.3 - 236.9例）。在22年的时间里，PTB患病率下降了61%。
