Milewska Magdalena, Sińska Beata, Sych Daria, Kucharska Alicja
Department of Human Nutrition, Faculty of Health Science, Medical University of Warsaw, Poland.
Pol Merkur Lekarski. 2015 Apr;38(226):206-10.
Postmenopausal period brings changes in body composition. Among the major alterations the tendency to decrease in fat free mass (FFM) and increase in the amount of fat mass (FM) are observed. Simultaneously loss of muscle mass and decline in muscle strength with the advancing age are observed. Coexistence of sarcopenia and obesity creates a new category of obesity - sarcopenic obesity (SO), which may cause numerous negative consequences. Therefore, clinicians attention should be drawn to this issue. Unfortunately clear criteria to its identification are lacking.
The aim of the present investigation was to determine the prevalence of sarcopenic obesity in postmenopausal women in depending on different definition.
Thirty two postmenopausal women (Group 1) and thirty one young, healthy women (Group 2) participated in the study. Within Group 1 SO was identified, while Group 2 was used for defining to cut-off points. All participants underwent body composition analysis by bioelectrical impedance. Additionally height, body weight and hand grip strength were measured. Sarcopenic obesity was defined by the combination of obesity and sarcopenia.
Using different criteria for SO identification diversified study results in the prevalence of SO were observed (21.87 to 84.37%). The highest percentage of SO persons was observed while using the Skeletal Mass Index (SMI) derived cut off score, with fat mass (FM%), the most inclusive. In contrast, the lowest number of sarcopenic obese cases were observed when FFMI based on own group cut-off point was used and in the case of using MMI derived cut-off point defined for French population.
Prevalence of sarcopenic obesity varied, depending on the used criteria. Due to discrepancies between the criteria of sarcopenic obesity identification, standardization of definition and muscle mass predictive equations are required. Development of reference values for Polish population should be undertaken.
绝经后期会带来身体成分的变化。在主要变化中，可观察到无脂肪体重（FFM）有下降趋势，而脂肪量（FM）增加。同时，随着年龄增长，肌肉量减少且肌肉力量下降。肌肉减少症和肥胖症并存形成了一种新的肥胖类型——肌肉减少性肥胖（SO），这可能会导致许多负面后果。因此，应引起临床医生对这个问题的关注。不幸的是，目前缺乏明确的识别标准。
本研究的目的是根据不同定义确定绝经后女性肌肉减少性肥胖的患病率。
32名绝经后女性（第1组）和31名年轻健康女性（第2组）参与了研究。在第1组中识别出SO，而第2组用于确定切点。所有参与者均通过生物电阻抗进行身体成分分析。此外，还测量了身高、体重和握力。肌肉减少性肥胖由肥胖症和肌肉减少症共同定义。
使用不同的SO识别标准，观察到SO患病率的研究结果存在差异（21.87%至84.37%）。使用骨骼质量指数（SMI）得出的切点分数，同时结合脂肪量（FM%），得出的SO患者百分比最高，涵盖范围最广。相比之下，当使用基于自身组切点的FFMI以及使用为法国人群定义的MMI得出的切点时，肌肉减少性肥胖病例数最少。
肌肉减少性肥胖的患病率因所用标准而异。由于肌肉减少性肥胖识别标准之间存在差异，需要对定义和肌肉量预测方程进行标准化。应制定波兰人群的参考值。
