Öztürk Zeynel Abidin, Türkbeyler İbrahim Halil, Abiyev Azer, Kul Seval, Edizer Bahadır, Yakaryılmaz Funda Datli, Soylu Gülçimen
Faculty of Medicine, Department of Internal Medicine, Division of Geriatric Medicine, Gaziantep University, Gaziantep, Turkey.
Faculty of Medicine, Department of Internal Medicine, Gaziantep University, Gaziantep, Turkey.
Intern Med J. 2018 Aug;48(8):973-981. doi: 10.1111/imj.13935.
Sarcopenia, obesity, and sarcopenic obesity are various features of the ageing process that can cause important health issues. The present study was undertaken to investigate the interrelationship between those body composition changes, including their clinical components and the quality-of-life variables.
A total of 423 individuals aged 65 years or older was included in this cross-sectional study. Sarcopenia was diagnosed according to The European Working Group on Sarcopenia in Older People criteria. Body composition parameters were measured with a bioelectrical impedance analyser, and Turkish population-based cut-off points were preferred for diagnosis of sarcopenia. Comprehensive geriatric assessment was performed on all patients. A logistic regression analysis was performed to identify important factors for sarcopenia and sarcopenic obesity.
The prevalence of sarcopenic, obese and sarcopenic obese subjects was 14%, 35% and 11% respectively. The lowest mean gait speed and hand grip strength values were seen in the sarcopenic obese group (0.6 ± 0.3 m/s and 19.7 ± 9.8 kg respectively). Sarcopenic obese participants were associated with the highest rate for fall risk. The scores for domains of health-related quality of life were worse in both obesity and sarcopenic obesity when compared to others. Body mass index (BMI), number of drugs used, total body fat ratio and geriatric depression scale-short form scores were negatively correlated with all dimensions of SF-36 quality-of-life scale.
Sarcopenia, obesity and sarcopenic obesity are associated with many negative health outcomes, such as high fall risk and low health-related quality of life in geriatric population.
肌肉减少症、肥胖症和肌少症性肥胖是衰老过程的不同特征，可导致重要的健康问题。本研究旨在调查这些身体成分变化之间的相互关系，包括其临床组成部分和生活质量变量。
本横断面研究共纳入423名65岁及以上的个体。根据欧洲老年人肌肉减少症工作组的标准诊断肌肉减少症。使用生物电阻抗分析仪测量身体成分参数，并采用基于土耳其人群的切点来诊断肌肉减少症。对所有患者进行综合老年评估。进行逻辑回归分析以确定肌肉减少症和肌少症性肥胖的重要因素。
肌肉减少症、肥胖症和肌少症性肥胖受试者的患病率分别为14%、35%和11%。肌少症性肥胖组的平均步速和握力值最低（分别为0.6±0.3米/秒和19.7±9.8千克）。肌少症性肥胖参与者的跌倒风险率最高。与其他组相比，肥胖症和肌少症性肥胖患者的健康相关生活质量领域得分均较差。体重指数（BMI）、用药数量、体脂率和老年抑郁量表简表得分与SF-36生活质量量表的所有维度均呈负相关。
肌肉减少症、肥胖症和肌少症性肥胖与许多负面健康结果相关，如老年人群中高跌倒风险和低健康相关生活质量。
