Department of Medicine, The University of Chicago, Chicago, IL.
Chest. 2015 May;147(5):1401-1412. doi: 10.1378/chest.14-1355.
The purpose of this article is to provide an update on evidence-based methods for mediastinal staging in patients with lung cancer. This is a review of the recently published studies and a summary of relevant guidelines addressing the role of CT scan, PET scan, endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA), and mediastinoscopy as pertinent to lung cancer staging and restaging. The focus is on how these diagnostic methods fit into the best algorithm for patients with chest imaging abnormalities suspected of malignant disease. Several studies, meta-analyses, and systematic reviews specifically targeted the role of PET scan, EBUS-TBNA, and mediastinoscopy for detecting mediastinal lymph node involvement in patients suffering from lung cancer. Based on the recommendations from the currently published guidelines, algorithms of care are proposed for staging and restaging of the mediastinum.
本文旨在提供肺癌纵隔分期循证方法的最新信息。这是对最近发表的研究的回顾，以及对相关指南的总结，这些指南涉及 CT 扫描、PET 扫描、支气管内超声引导经支气管针吸活检（EBUS-TBNA）和纵隔镜检查在肺癌分期和再分期中的作用。重点是这些诊断方法如何适用于疑似恶性疾病的胸部影像学异常患者的最佳算法。几项研究、荟萃分析和系统评价专门针对 PET 扫描、EBUS-TBNA 和纵隔镜检查在检测肺癌患者纵隔淋巴结受累中的作用。根据目前发表的指南的建议，提出了纵隔分期和再分期的护理算法。
