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意大利在校青少年中的沙眼衣原体基因型

Chlamydia trachomatis genotypes in school adolescents, Italy.

作者信息

Stefanelli Paola, Sulis Giorgia, Renna Giovanna, Gargiulo Franco, Zanotti Paola, Capelli Michela, De Francesco Maria Antonia, Donato Francesco, Pecorelli Sergio, Matteelli Alberto

机构信息

Department of Infectious, Parasitic and Immuno-mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

University Division of Infectious and Tropical Diseases, Spedali Civili General Hospital, University of Brescia, Brescia, Italy.

出版信息

Infection. 2015 Dec;43(6):739-41. doi: 10.1007/s15010-015-0787-5. Epub 2015 May 5.

DOI:10.1007/s15010-015-0787-5
PMID:25940434
Abstract

Chlamydia trachomatis genogroups using ompA and multilocus sequence typing (MLST) were determined in consecutive isolates from school students aged 18 or older in the district of Brescia, Italy, 2012-2013. Among 40 samples, 4 ompA genovars and 18 STs were identified. Genovar E predominated (70 %) including five STs derived from ST59 (29 % of all isolates). This study, combining ompA and MLST typing of C. trachomatis school teenagers, suggests limited mixing and sexual interchange in this population.

摘要

2012 - 2013年,在意大利布雷西亚地区对18岁及以上在校学生的连续分离株进行了沙眼衣原体基因组群的ompA基因分型和多位点序列分型(MLST)。在40个样本中,鉴定出4种ompA基因变种和18种序列型。基因变种E占主导(70%),包括源自ST59的5种序列型(占所有分离株的29%)。这项结合了沙眼衣原体在校青少年ompA基因分型和MLST分型的研究表明,该人群中的混合感染和性传播有限。

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本文引用的文献

1
Chlamydia trachomatis genovar distribution in clinical urogenital specimens from Tunisian patients: high prevalence of C. trachomatis genovar E and mixed infections.沙眼衣原体血清型在突尼斯患者泌尿生殖道临床标本中的分布:沙眼衣原体血清型 E 及混合感染的高流行率。
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Chlamydia trachomatis serovar distribution and other sexually transmitted coinfections in subjects attending an STD outpatients clinic in Italy.意大利一家性传播疾病门诊患者中沙眼衣原体血清型分布及其他性传播合并感染情况
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Multilocus sequence typing of genital Chlamydia trachomatis in Norway reveals multiple new sequence types and a large genetic diversity.
挪威生殖器沙眼衣原体的多位点序列分型显示出多种新的序列类型和高度的遗传多样性。
PLoS One. 2012;7(3):e34452. doi: 10.1371/journal.pone.0034452. Epub 2012 Mar 28.
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J Clin Microbiol. 2011 Aug;49(8):2844-53. doi: 10.1128/JCM.00128-11. Epub 2011 Jun 8.
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Characterisation of Chlamydia trachomatis by ompA sequencing and multilocus sequence typing in a Swedish county before and after identification of the new variant.在鉴定出新变体前后,对瑞典一个县的沙眼衣原体进行 ompA 测序和多位点序列分型的特征描述。
Sex Transm Infect. 2010 Feb;86(1):56-60. doi: 10.1136/sti.2009.037572. Epub 2009 Oct 16.
7
Predicting phenotype and emerging strains among Chlamydia trachomatis infections.预测沙眼衣原体感染的表型和新菌株。
Emerg Infect Dis. 2009 Sep;15(9):1385-94. doi: 10.3201/eid1509.090272.
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A Chlamydia trachomatis strain with a 377-bp deletion in the cryptic plasmid causing false-negative nucleic acid amplification tests.一株沙眼衣原体菌株,其隐蔽质粒存在377碱基对的缺失,导致核酸扩增检测出现假阴性。
Sex Transm Dis. 2007 May;34(5):255-6. doi: 10.1097/OLQ.0b013e31805ce2b9.
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High-resolution genotyping of Chlamydia trachomatis strains by multilocus sequence analysis.通过多位点序列分析对沙眼衣原体菌株进行高分辨率基因分型。
J Clin Microbiol. 2007 May;45(5):1410-4. doi: 10.1128/JCM.02301-06. Epub 2007 Feb 28.
10
Characterization of ompA genotypes by sequence analysis of DNA from all detected cases of Chlamydia trachomatis infections during 1 year of contact tracing in a Swedish County.在瑞典一个县进行为期1年的接触者追踪期间,通过对所有检测到的沙眼衣原体感染病例的DNA进行序列分析来鉴定ompA基因型。
J Clin Microbiol. 2004 Apr;42(4):1641-7. doi: 10.1128/JCM.42.4.1641-1647.2004.