Kofoed Christina L F, Christensen Jane, Dragsted Lars O, Tjønneland Anne, Roswall Nina
Danish Cancer Research Center, Danish Cancer Society,Strandboulevarden 49,DK-2100Copenhagen Ø,Denmark.
Department of Nutrition,Exercise and Sports, Faculty of Life Science, University of Copenhagen,Nørre Allé 51,DK-2200Copenhagen N,Denmark.
Br J Nutr. 2015 Jun 28;113(12):1993-2000. doi: 10.1017/S0007114515001440. Epub 2015 May 5.
The prevalence of dietary supplement use varies largely among populations, and previous studies have indicated that it is high in the Danish population compared with other European countries. The diversity in supplement use across countries indicates that cultural and environmental factors could influence the use of dietary supplements. Only few studies investigating the use of dietary supplements have been conducted in the Danish population. The present cross-sectional study is based on 54,948 Danes, aged 50-64 years, who completed self-administrated questionnaires on diet, dietary supplements and lifestyle between 1993 and 1997. A health index including smoking, physical activity, alcohol and diet, and a metabolic risk index including waist circumference, urinary glucose and measured hypertension were constructed. Logistic regression was used to investigate these determinants in relation to the intake of dietary supplements. We found that 71 % of the participants were dietary supplement users; female sex, older age groups and higher educated participants were more likely to be users of any dietary supplements. One additional point in the health index was associated with 19, 16 and 9 % higher likelihood of being user of any, more common and less common supplements, respectively. In the metabolic risk index, one additional point was associated with 17 and 16 % lower likelihood of being user of any supplement and more common supplements, respectively. No significant association was found for less common supplement use. In conclusion, those with the healthiest lifestyle were more likely to use dietary supplements. Thus, lifestyle and dietary composition should be considered as confounders on supplement use and health outcomes.
膳食补充剂的使用 prevalence 在不同人群中差异很大,先前的研究表明,与其他欧洲国家相比,丹麦人群中其使用率较高。各国补充剂使用情况的差异表明,文化和环境因素可能会影响膳食补充剂的使用。在丹麦人群中,仅有少数研究调查了膳食补充剂的使用情况。本横断面研究基于54948名年龄在50至64岁之间的丹麦人,他们在1993年至1997年间完成了关于饮食、膳食补充剂和生活方式的自我管理问卷。构建了一个包括吸烟、身体活动、饮酒和饮食的健康指数,以及一个包括腰围、尿糖和测量高血压的代谢风险指数。使用逻辑回归来研究这些决定因素与膳食补充剂摄入量的关系。我们发现,71%的参与者是膳食补充剂使用者;女性、年龄较大的群体和受教育程度较高的参与者更有可能使用任何膳食补充剂。健康指数每增加一分,使用任何、较常见和较不常见补充剂的可能性分别增加19%、16%和9%。在代谢风险指数中,每增加一分,使用任何补充剂和较常见补充剂的可能性分别降低17%和16%。对于较不常见的补充剂使用,未发现显著关联。总之,生活方式最健康的人更有可能使用膳食补充剂。因此,生活方式和饮食组成应被视为补充剂使用和健康结果的混杂因素。 (注:原文中“prevalence”未翻译,可能是拼写有误,推测应为“使用率”之类的意思,需根据上下文进一步确认。)