Influenza Division.
Centro de Estudios en Salud, Universidad del Valle de Guatemala, Guatemala City.
J Infect Dis. 2015 Nov 15;212(10):1600-3. doi: 10.1093/infdis/jiv265. Epub 2015 May 5.
We evaluated the added value of collecting both nasal and oropharyngeal swabs, compared with collection of nasal swabs alone, for detection of common respiratory viruses by reverse transcription-polymerase chain reaction in hospitalized children aged <10 years. Nasal swabs had equal or greater sensitivity than oropharyngeal swabs for detection of respiratory syncytial virus, adenovirus, human metapneumovirus, rhinovirus, and influenza virus but not parainfluenza virus. The addition of an oropharyngeal swab, compared with use of a nasal swab alone, increased the frequency of detection of each respiratory virus by no more than 10% in children aged <10 years.
我们评估了与单独采集鼻拭子相比，同时采集鼻拭子和咽拭子对 10 岁以下住院患儿进行逆转录-聚合酶链反应检测常见呼吸道病毒的附加价值。鼻拭子检测呼吸道合胞病毒、腺病毒、人偏肺病毒、鼻病毒和流感病毒的敏感性与咽拭子相等或更高，但不能检测副流感病毒。与单独使用鼻拭子相比，增加咽拭子的采集，在 10 岁以下儿童中，每种呼吸道病毒的检测频率最多增加不超过 10%。
