Andrews P J, Choudhury N, Takhar A, Poirrier A L, Jacques T, Randhawa P S
Department of Rhinology and Facial Plastic Surgery, Royal National Throat Nose and Ear Hospital, London, UK.
The Ear Institute, UCL, London, UK.
Clin Otolaryngol. 2015 Dec;40(6):698-703. doi: 10.1111/coa.12455.
To assess the reliability of nasal inspiratory peak flow (NIPF) in providing a clinically accurate objective measure following functional septorhinoplasty by comparing it to the validated disease-specific quality-of-life questionnaire, SNOT-22. Studies so far have demonstrated poor correlation between bilateral NIPF and symptom-specific nasal questionnaires following septorhinoplasty.
To perform a prospective comparative analysis between NIPF and the validated disease-specific quality-of-life questionnaire SNOT-22 and to determine whether a correlation exists following septorhinoplasty surgery.
The Royal National Throat Nose and Ear Hospital, London.
A total of 122 patients (78 males, 44 females; mean age 33.5 ± 12.2 years) were recruited from the senior authors rhinology clinic and underwent functional septorhinoplasty surgery.
Preoperative and postoperative nasal inspiratory peak flow (NIPF) measurements were performed in addition to the completion of three subjective quality-of-life and symptom assessment tool questionnaires; Sinonasal Outcome Test 22 (SNOT-22), Nasal Obstruction Symptom Evaluation (NOSE) and Visual Analogue Scale (VAS: 0-10).
The mean preoperative NIPF was 88.2 L/min, and the postoperative value was 101.6 L/min and showed a significant improvement following surgery (P = 0.0064). The mean total SNOT-22 score improved significantly from 48.6 to 26.6 (P < 0.0001); the NOSE score from 14.1 to 6.6 (P < 0.0001); and the Visual Analogue Scale (VAS) blockage score from 6.9 to 3.2 (P < 0.0001). All individual domains assessed showed improvements postoperatively, but no correlation was found between the NIPF and SNOT-22 score. Equally, we did not find a correlation between NIPF and the symptom-specific NOSE questionnaire and the nasal blockage domain on the Visual Analogue Scale (VAS) scale.
We have demonstrated that NIPF does not correlate with the SNOT-22 disease-specific questionnaire, although both outcomes significantly improve postoperatively. At present, we are still lacking a clinically accurate objective measure of nasal function for the evaluation of patients undergoing septorhinoplasty surgery.
通过将鼻吸气峰流量（NIPF）与经过验证的疾病特异性生活质量问卷SNOT-22进行比较，评估其在功能性鼻中隔成形术后提供临床准确客观测量值的可靠性。迄今为止的研究表明，鼻中隔成形术后双侧NIPF与症状特异性鼻问卷之间的相关性较差。
对NIPF与经过验证的疾病特异性生活质量问卷SNOT-22进行前瞻性比较分析，并确定鼻中隔成形术后是否存在相关性。
伦敦皇家国立耳鼻喉医院。
从资深作者的鼻科诊所招募了总共122名患者（78名男性，44名女性；平均年龄33.5±12.2岁），并接受了功能性鼻中隔成形手术。
除了完成三份主观生活质量和症状评估工具问卷外，还进行术前和术后鼻吸气峰流量（NIPF）测量；鼻窦结局测试22（SNOT-22）、鼻阻塞症状评估（NOSE）和视觉模拟量表（VAS：0-10）。
术前平均NIPF为88.2升/分钟，术后值为101.6升/分钟，术后有显著改善（P = 0.0064）。SNOT-22总分从48.6显著改善至26.6（P < 0.0001）；NOSE评分从14.1降至6.6（P < 0.0001）；视觉模拟量表（VAS）阻塞评分从6.9降至3.2（P < 0.0001）。所有评估的个体领域术后均有改善，但未发现NIPF与SNOT-22评分之间存在相关性。同样，我们也未发现NIPF与症状特异性NOSE问卷以及视觉模拟量表（VAS）量表上的鼻阻塞领域之间存在相关性。
我们已经证明，尽管两种结果术后均有显著改善，但NIPF与SNOT-22疾病特异性问卷不相关。目前，我们仍然缺乏一种临床准确的客观鼻功能测量方法来评估接受鼻中隔成形手术的患者。
