Randhawa P S, Watson N, Lechner M, Ritchie L, Choudhury N, Andrews P J
Department of Rhinology and Facial Plastic Surgery, Royal National Throat Nose and Ear Hospital, London, UK.
Clin Otolaryngol. 2016 Feb;41(1):15-20. doi: 10.1111/coa.12463.
To assess olfactory outcomes in patients undergoing septorhinoplasty surgery in our unit.
Prospective cohort study.
The Royal National Throat Nose and Ear Hospital, London.
Forty-three patients undergoing functional septorhinoplasty (Males = 26; mean age = 34.1 ± 12.2) were recruited into the study.
The primary outcome of olfactory function was assessed using 'Sniffin sticks'. Our secondary outcomes were assessment of patient quality of life using the disease specific Sino-nasal Outcome Test-23 questionnaire (SNOT-23) and a visual analogue scale for sense of smell. These measures were repeated at 12 weeks post operatively.
There was a significant change in the Sniffin' sticks score post-operatively (8.3 versus 9.6; P < 0.001). The SNOT-23 score also showed a significant improvement post-operatively (53.5 versus 40.4; P < 0.001). A significant improvement was not found in the smell/taste question (question 21) of the SNOT-23 questionnaire as well as the visual analogue scale for sense of smell. A difference in olfactory outcome was not found between open versus closed approaches, primary versus revision surgery and traumatic versus non traumatic cases.
The results show a measured significant improvement in olfaction following functional Septorhinoplasty but not a subjective improvement in the patients perception of their sense of smell and hence not a clinically significant difference. The reasons for the measured improvement are not clear and are likely to be multifactorial.
评估在我们科室接受鼻中隔鼻成形术患者的嗅觉结果。
前瞻性队列研究。
伦敦皇家国立耳鼻喉医院。
43例接受功能性鼻中隔鼻成形术的患者(男性26例;平均年龄 = 34.1 ± 12.2)被纳入研究。
使用“嗅觉棒”评估嗅觉功能的主要结果。我们的次要结果是使用疾病特异性的鼻窦结局测试-23问卷(SNOT-23)和嗅觉视觉模拟量表评估患者的生活质量。这些测量在术后12周重复进行。
术后嗅觉棒评分有显著变化(8.3对9.6;P < 0.001)。SNOT-23评分术后也显示出显著改善(53.5对40.4;P < 0.001)。SNOT-23问卷的嗅觉/味觉问题(问题21)以及嗅觉视觉模拟量表未发现显著改善。开放与闭合手术方式、初次手术与翻修手术以及创伤性与非创伤性病例之间在嗅觉结果上未发现差异。
结果显示功能性鼻中隔鼻成形术后嗅觉有适度的显著改善,但患者对嗅觉的主观感受没有改善,因此没有临床显著差异。测量到改善的原因尚不清楚,可能是多因素的。