Johnson M I, Ashton C H, Bousfield D R, Thompson J W
Clinical Psychopharmacology Unit, Department of Pharmacological Sciences, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH U.K.
Pain. 1989 Nov;39(2):231-236. doi: 10.1016/0304-3959(89)90010-9.
The efficacy of transcutaneous electrical nerve stimulation (TENS) in producing analgesia in cold-induced pain was assessed using a range of 5 stimulating frequencies (10 Hz, 20 Hz, 40 Hz, 80 Hz and 160 Hz) in 83 normal healthy subjects. TENS significantly elevated ice pain threshold when compared with sham and control groups. TENS frequencies between 20 and 80 Hz produced greatest analgesia, while frequencies below and above this level (10 Hz and 160 Hz), although significantly elevating ice pain threshold, produced effects of a lesser magnitude. The frequency of pulse delivery was the governing factor as no significant differences in stimulus intensity were observed across the treatment groups. Measurement of ice pain tolerance was found to be unreliable under the present conditions. No significant relationships were observed between personality variables as measured by Eysenck Personality Questionnaires and the degree of TENS response.
在83名正常健康受试者中，使用5种刺激频率（10赫兹、20赫兹、40赫兹、80赫兹和160赫兹）评估经皮电神经刺激（TENS）对冷诱导疼痛产生镇痛作用的效果。与假刺激组和对照组相比，TENS显著提高了冰痛阈值。20至80赫兹之间的TENS频率产生的镇痛效果最佳，而低于和高于此水平的频率（10赫兹和160赫兹）虽然显著提高了冰痛阈值，但其产生的效果程度较小。脉冲传递频率是主要因素，因为各治疗组在刺激强度方面未观察到显著差异。发现在当前条件下，冰痛耐受性的测量不可靠。通过艾森克人格问卷测量的人格变量与TENS反应程度之间未观察到显著关系。
