Xu Yunzhi, Chen Guangjie
Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Immunology, Shanghai 200025, China.
Mediators Inflamm. 2015;2015:246126. doi: 10.1155/2015/246126. Epub 2015 Apr 5.
Mast cells are important in innate immune system. They have been appreciated as potent contributors to allergic reaction. However, increasing evidence implicates the important role of mast cells in autoimmune disease like rheumatoid arthritis and multiple sclerosis. Here we review the current stage of knowledge about mast cells in autoimmune diseases.
肥大细胞在固有免疫系统中很重要。它们被认为是过敏反应的有力促成因素。然而，越来越多的证据表明肥大细胞在类风湿性关节炎和多发性硬化症等自身免疫性疾病中发挥着重要作用。在此，我们综述了目前关于自身免疫性疾病中肥大细胞的知识现状。
