Passos Susane Müller Klug, Souza Luciano Dias de Mattos
Cad Saude Publica. 2015 Apr;31(4):800-14. doi: 10.1590/0102-311x00000514.
This cross-sectional study evaluated the quality of life and its associated factors among people living with HIV/AIDS at a regional reference center for the treatment of HIV/AIDS in southern Brazil. WHOQOL-HIV Bref, ASSIST 2.0, HAD Scale, and a questionnaire were used to assess 625 participants on quality of life, clinical and sociodemographic characteristics, drug use, depression and anxiety. Multivariate analysis was performed through linear regression. The lowest results for quality of life were associated with being female, age (< 47 years), low education levels, low socioeconomic class, unemployment, not having a stable relationship, signs of anxiety and depression, abuse or addiction of psychoactive substances, lack of perceived social support, never taking antiretroviral medication, lipodystrophy, comorbidities, HIV related hospitalizations and a CD4+ cell count less than 350. Psychosocial factors should be included in the physical and clinical evaluation given their strong association with quality of life domains.
这项横断面研究评估了巴西南部一家艾滋病治疗区域参考中心的艾滋病毒/艾滋病感染者的生活质量及其相关因素。使用世界卫生组织生活质量测定量表HIV简表、酒精、吸烟和物质使用情况筛查工具2.0、医院焦虑抑郁量表以及一份问卷，对625名参与者的生活质量、临床和社会人口学特征、药物使用、抑郁和焦虑情况进行了评估。通过线性回归进行多变量分析。生活质量得分最低与女性、年龄（<47岁）、教育水平低、社会经济阶层低、失业、没有稳定关系、焦虑和抑郁迹象、精神活性物质滥用或成瘾、缺乏感知到的社会支持、从未服用抗逆转录病毒药物、脂肪代谢障碍、合并症、与艾滋病毒相关的住院治疗以及CD4+细胞计数低于350有关。鉴于心理社会因素与生活质量领域密切相关，应将其纳入身体和临床评估。
