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对柬埔寨接受抗逆转录病毒治疗的艾滋病毒/艾滋病成年患者生活质量的评估:简短报告。

An evaluation of quality of life among Cambodian adults living with HIV/AIDS and using antiretroviral therapy: a short report.

作者信息

Yang Youngran, Thai Sopheak, Choi Jongsan

机构信息

a School of Nursing , Research Institute of Nursing Science, Chonbuk National University , Jeonju , South Korea.

b Sihanouk Hospital CENTER of HOPE , Phnom Penh , Cambodia.

出版信息

AIDS Care. 2016 Dec;28(12):1546-1550. doi: 10.1080/09540121.2016.1192100. Epub 2016 Jun 10.

Abstract

The aim of this study was to evaluate quality of life (QOL) and analyze its determinants among Cambodian adults living with HIV/AIDS who are on antiretroviral therapy (ART). A cross-sectional study was conducted using convenience sampling to select 150 adults 18 years of age or older from the patient population at the HIV/AIDS care hospital in Phnom Penh, Cambodia. QOL was assessed using the World Health Organization Quality of Life HIV BREF; socio-demographic characteristics, time elapsed since HIV diagnosis, months on ART, CD4 cell count, family and community support, depression, and anxiety were included in the survey. Results of the multiple regression analysis indicate that positive predictors of QOL included being female, being less 40 years old, having a household monthly income greater than 300 USD, having an education beyond the secondary level, or being employed. However, time elapsed since HIV diagnosis and duration of ART were not significantly associated with QOL and CD4 cell count and the World Health Organization clinical stage had little association with QOL. Perceiving oneself as healthy and happy and reporting no depression or anxiety were associated with a positive QOL. These findings suggest the importance of group-specific interventions to improve the QOL for those people living with HIV/AIDS in Cambodia who are male, have a low household income or education level, are unemployed, or are anxious or depressed.

摘要

本研究的目的是评估接受抗逆转录病毒治疗(ART)的柬埔寨成年艾滋病毒/艾滋病患者的生活质量(QOL)并分析其决定因素。采用便利抽样法进行了一项横断面研究,从柬埔寨金边艾滋病毒/艾滋病护理医院的患者群体中选取了150名18岁及以上的成年人。使用世界卫生组织生活质量艾滋病毒简表评估生活质量;调查内容包括社会人口学特征、自艾滋病毒诊断以来的时间、接受ART的月数、CD4细胞计数、家庭和社区支持、抑郁和焦虑。多元回归分析结果表明,生活质量的积极预测因素包括女性、年龄小于40岁、家庭月收入超过300美元、受过中等以上教育或有工作。然而,自艾滋病毒诊断以来的时间和ART持续时间与生活质量无显著关联,CD4细胞计数和世界卫生组织临床分期与生活质量关联不大。自我感觉健康快乐且无抑郁或焦虑与积极的生活质量相关。这些发现表明,针对柬埔寨男性艾滋病毒/艾滋病患者、家庭收入或教育水平低、失业、焦虑或抑郁的人群,进行特定群体干预以改善其生活质量具有重要意义。

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