格鲁吉亚Xpert(®) MTB/RIF检测与GenoType(®) MTBDRplus检测的比较
A comparison of the Xpert(®) MTB/RIF and GenoType(®) MTBDRplus assays in Georgia.
作者信息
Bablishvili N, Tukvadze N, Avaliani Z, Blumberg H M, Kempker R R
机构信息
National Center for Tuberculosis and Lung Diseases, Tbilisi, Georgia.
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
出版信息
Int J Tuberc Lung Dis. 2015 Jun;19(6):676-8. doi: 10.5588/ijtld.14.0867.
Abstract
Few studies have directly compared the performance of rapid molecular diagnostic tests for tuberculosis (TB). We found that the commercially available molecular diagnostic tests Xpert(®) MTB/RIF and GenoType(®) MTBDRplus both provided timely and accurate results compared to conventional phenotypic tests in detecting TB and rifampicin resistance.
摘要
很少有研究直接比较过结核病（TB）快速分子诊断检测的性能。我们发现，与传统表型检测相比，市售的分子诊断检测Xpert(®) MTB/RIF和GenoType(®) MTBDRplus在检测结核病和利福平耐药性方面均能提供及时且准确的结果。
相似文献
1
A comparison of the Xpert(®) MTB/RIF and GenoType(®) MTBDRplus assays in Georgia.格鲁吉亚Xpert(®) MTB/RIF检测与GenoType(®) MTBDRplus检测的比较
Int J Tuberc Lung Dis. 2015 Jun;19(6):676-8. doi: 10.5588/ijtld.14.0867.
2
Comparison of Xpert MTB/RIF with other nucleic acid technologies for diagnosing pulmonary tuberculosis in a high HIV prevalence setting: a prospective study.在高 HIV 流行地区比较 Xpert MTB/RIF 与其他核酸技术诊断肺结核的前瞻性研究。
PLoS Med. 2011 Jul;8(7):e1001061. doi: 10.1371/journal.pmed.1001061. Epub 2011 Jul 26.
3
A novel automatic molecular test for detection of multidrug resistance tuberculosis in sputum specimen: A case control study.一种用于检测痰标本中耐多药结核病的新型自动分子检测方法：一项病例对照研究。
Tuberculosis (Edinb). 2017 Jul;105:9-12. doi: 10.1016/j.tube.2017.03.008. Epub 2017 Mar 29.
4
Diagnostic accuracy and usefulness of the Genotype MTBDRplus assay in diagnosing multidrug-resistant tuberculosis in Cameroon? a cross-sectional study.基因分型MTBDRplus检测法在喀麦隆诊断耐多药结核病中的诊断准确性及实用性？一项横断面研究。
BMC Infect Dis. 2017 May 31;17(1):379. doi: 10.1186/s12879-017-2489-3.
5
Performance of the MTBDRsl assay in Georgia.格鲁吉亚的 MTBDRsl 检测试剂盒性能。
Int J Tuberc Lung Dis. 2014 Feb;18(2):233-9. doi: 10.5588/ijtld.13.0468.
6
Evaluation of the GenoType(®) MTBDRplus line probe assay on sputum-positive samples in routine settings in China.在中国常规环境下对痰涂片阳性样本进行GenoType(®) MTBDRplus线性探针检测的评估。
Int J Tuberc Lung Dis. 2014 Sep;18(9):1034-9. doi: 10.5588/ijtld.13.0857.
7
Comparison of targeted next-generation sequencing and the Xpert MTB/RIF assay for detection of in clinical isolates and sputum specimens.比较靶向下一代测序和 Xpert MTB/RIF assay 检测临床分离株和痰标本中的 。
Microbiol Spectr. 2024 May 2;12(5):e0409823. doi: 10.1128/spectrum.04098-23. Epub 2024 Apr 11.
8
Evaluation of the MTBDRplus 2.0 assay for the detection of multidrug resistance among persons with presumptive pulmonary TB in China.评估 MTBDRplus 2.0 检测中国疑似肺结核患者耐多药的应用。
Sci Rep. 2017 Jun 13;7(1):3364. doi: 10.1038/s41598-017-03473-7.
9
Molecular diagnosis of MDR-TB using GenoType MTBDRplus 96 assay in Ibadan, Nigeria.在尼日利亚伊巴丹使用GenoType MTBDRplus 96检测法对耐多药结核病进行分子诊断。
Niger J Physiol Sci. 2013 Dec 20;28(2):187-91.
10
Diagnostic accuracy and turnaround time of the Xpert MTB/RIF assay in routine clinical practice.Xpert MTB/RIF assay 在常规临床实践中的诊断准确性和周转时间。
PLoS One. 2013 Oct 29;8(10):e77456. doi: 10.1371/journal.pone.0077456. eCollection 2013.
引用本文的文献
1
The performance of Xpert MTB/RIF and MTBDRplus within a Programmatic setting at TB Laboratory in Rio de Janeiro, Brazil.Xpert MTB/RIF 和 MTBDRplus 在巴西里约热内卢结核病实验室规划环境中的表现。
Rev Soc Bras Med Trop. 2024 Sep 13;57:e004162024. doi: 10.1590/0037-8682-0167-2024. eCollection 2024.
2
Effectiveness of Xpert MTB/RIF and the Line Probe Assay tests for the rapid detection of drug-resistant tuberculosis in the Central African Republic.Xpert MTB/RIF和线性探针检测法在中非共和国快速检测耐多药结核病中的有效性。
PLOS Glob Public Health. 2023 May 1;3(5):e0001847. doi: 10.1371/journal.pgph.0001847. eCollection 2023.
3
Impact of molecular diagnostic tests on diagnostic and treatment delays in tuberculosis: a systematic review and meta-analysis.分子诊断检测对结核病诊断和治疗延迟的影响：系统评价和荟萃分析。
BMC Infect Dis. 2022 Dec 14;22(1):940. doi: 10.1186/s12879-022-07855-9.
4
Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in adults, irrespective of signs or symptoms.Xpert MTB/RIF 和 Xpert Ultra 检测用于筛查成人肺结核和利福平耐药，无论有无症状。
Cochrane Database Syst Rev. 2021 Mar 23;3(3):CD013694. doi: 10.1002/14651858.CD013694.pub2.
5
Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis.Xpert Ultra 与 Xpert MTB/RIF 检测疑似肺结核成人肺结核和利福平耐药性的比较。
Cochrane Database Syst Rev. 2021 Feb 22;2:CD009593. doi: 10.1002/14651858.CD009593.pub5.
6
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in adults.Xpert MTB/RIF Ultra 检测和 Xpert MTB/RIF 检测在成人肺外结核和利福平耐药检测中的应用。
Cochrane Database Syst Rev. 2021 Jan 15;1(1):CD012768. doi: 10.1002/14651858.CD012768.pub3.
7
Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults.用于成人肺结核和利福平耐药性检测的Xpert MTB/RIF及Xpert MTB/RIF Ultra检测法
Cochrane Database Syst Rev. 2019 Jun 7;6(6):CD009593. doi: 10.1002/14651858.CD009593.pub4.
8
Pulmonary function and respiratory health after successful treatment of drug-resistant tuberculosis.耐药结核病成功治疗后的肺功能和呼吸健康。
Int J Infect Dis. 2019 May;82:66-72. doi: 10.1016/j.ijid.2019.02.039. Epub 2019 Mar 5.
9
Xpert MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance.用于肺外结核病和利福平耐药性的Xpert MTB/RIF检测
Cochrane Database Syst Rev. 2018 Aug 27;8(8):CD012768. doi: 10.1002/14651858.CD012768.pub2.
10
Impact of and Mutations in Improving Detection of Second-Line-Drug Resistance among Mycobacterium tuberculosis Isolates from Georgia.格鲁吉亚结核分枝杆菌分离株二线耐药中 及 突变的影响。
Antimicrob Agents Chemother. 2017 Aug 24;61(9). doi: 10.1128/AAC.01921-16. Print 2017 Sep.
本文引用的文献
1
Significant clinical impact of a rapid molecular diagnostic test (Genotype MTBDRplus assay) to detect multidrug-resistant tuberculosis.一种用于检测耐多药结核病的快速分子诊断检测方法（基因型MTBDRplus检测法）具有显著的临床影响。
Clin Infect Dis. 2014 Dec 1;59(11):1559-66. doi: 10.1093/cid/ciu631. Epub 2014 Aug 4.
2
Comparison of Xpert MTB/RIF with line probe assay for detection of rifampin-monoresistant Mycobacterium tuberculosis.Xpert MTB/RIF与线性探针分析检测利福平单耐药结核分枝杆菌的比较
J Clin Microbiol. 2014 Jun;52(6):1846-52. doi: 10.1128/JCM.03005-13. Epub 2014 Mar 19.
3
Clinical characteristics and treatment outcomes of patients with low- and high-concentration isoniazid-monoresistant tuberculosis.低浓度和高浓度异烟肼单耐药结核病患者的临床特征及治疗结果
PLoS One. 2014 Jan 22;9(1):e86316. doi: 10.1371/journal.pone.0086316. eCollection 2014.
4
Challenges to the global control of tuberculosis.全球结核病控制面临的挑战。
Respirology. 2013 May;18(4):596-604. doi: 10.1111/resp.12067.
5
Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults.用于检测成人肺结核和利福平耐药性的Xpert® MTB/RIF检测
Cochrane Database Syst Rev. 2013 Jan 31(1):CD009593. doi: 10.1002/14651858.CD009593.pub2.
6
The diagnostic performance of the GenoType MTBDRplus version 2 line probe assay is equivalent to that of the Xpert MTB/RIF assay.GenoType MTBDRplus 版本 2 线探针杂交检测法的诊断性能与 Xpert MTB/RIF 检测法相当。
J Clin Microbiol. 2012 Nov;50(11):3712-6. doi: 10.1128/JCM.01958-12. Epub 2012 Sep 12.
7
Use of a molecular diagnostic test in AFB smear positive tuberculosis suspects greatly reduces time to detection of multidrug resistant tuberculosis.在 AFB 涂片阳性的结核病疑似病例中使用分子诊断检测可大大缩短发现耐多药结核病的时间。
PLoS One. 2012;7(2):e31563. doi: 10.1371/journal.pone.0031563. Epub 2012 Feb 9.
8
Mechanisms of drug resistance in Mycobacterium tuberculosis.结核分枝杆菌耐药机制。
Int J Tuberc Lung Dis. 2009 Nov;13(11):1320-30.
Zotero 插件