Butenko G E, Ivanova D I, Gankevich D E, Besarabchik I P
Probl Tuberk. 1989(10):26-9.
To elucidate the role of pneumonia in pathogenesis of reactivation of residual tuberculous lesions, time courses of clinicoroentgenological and immunological indices for a period of 3 to 5 years before detection of active tuberculosis were studied. Nonspecific bronchopulmonary aggravations progressing by the type of acute, persisting or abscessing pneumonia have many features providing their consideration as nonspecific "masks" of the specific process progression. The features are: localization, clinical picture, disease process, time course increasing of the host specific sensitization, hyperergic character of reactions to intracutaneous tests with tuberculin and BCG vaccine, signs of specific endobronchitis, no effect of nonspecific treatment and favourable time course of the process under the effect of specific antibacterial therapy.
为阐明肺炎在残留结核病灶再激活发病机制中的作用,我们研究了在活动性肺结核检测前3至5年期间临床放射学和免疫学指标的时间进程。以急性、持续性或脓肿性肺炎类型进展的非特异性支气管肺加重具有许多特征,使其可被视为特定病程进展的非特异性“伪装”。这些特征包括:定位、临床表现、疾病进程、宿主特异性致敏的时间进程增加、对结核菌素和卡介苗皮内试验反应的超敏特性、特异性细支气管炎的体征、非特异性治疗无效以及在特异性抗菌治疗作用下病程的良好时间进程。