Sirenko I A, Marchenko O Iu, Pilipenko O N
Probl Tuberk. 1998(6):16-8.
Variability of tuberculin reactions in adolescents may be represented by changes of a negative tuberculin test to a positive or false one, then to a positive test. Adolescents primarily infected with tuberculosis have predisposing factors: inadequate immunoprophylaxis contact with tuberculosis patients, discord in physical development, hyperergic sensitivity to tuberculin, which can determine a further course of tuberculosis infection. The variability of tuberculin reactions in adolescents is characterized by changed immunological responsiveness as higher immunospecific parameters and lower nonspecific responsiveness parameters, as well as decreased attention; there is a trend for frequent development of primary infection in persons having character accentuation. The aforesaid allows the variability of tuberculin reactions to be regarded as "minor disease".
青少年结核菌素反应的变异性可能表现为结核菌素试验从阴性变为阳性或假阳性，然后再变为阳性。初次感染结核病的青少年有一些易感因素：免疫预防不足、与结核病患者接触、身体发育不协调、对结核菌素过敏，这些因素可决定结核病感染的进一步发展过程。青少年结核菌素反应的变异性表现为免疫反应性改变，即较高的免疫特异性参数和较低的非特异性反应性参数，以及注意力下降；性格突出的人有原发感染频繁发生的趋势。上述情况使得结核菌素反应的变异性可被视为“轻症疾病”。
