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[与慢性酒精中毒相关的肺结核发病率及这些疾病的综合治疗]

[Incidence of pulmonary tuberculosis associated with chronic alcoholism and a complex treatment of those diseases].

作者信息

Rudoĭ N M, Pilipchuk N S, Stadnikova A V, Dzhokhadze V A

出版信息

Probl Tuberk. 1989(10):3-7.

PMID:2594712
Abstract

It was shown that the prevalence of alcoholism among pulmonary tuberculosis patients was high and the outcomes of both the diseases proceeding in the presence of lowered immunity were often unfavourable, including the results of long-term follow-ups. The use of a specially constructed instrument for investigating the neurodynamic characteristics of the cerebral cortex and determination of gamma-glutamyl transpeptidase in the serum promoted diagnosis of prenosological entities of alcoholism. Higher efficacy of alcoholism treatment in the patients with tuberculosis was achieved with narcotic psychotherapy using the mixture of nitrous oxide and oxygen, esperal implantation and application of rifusal, a new preparation, as well as application of extracorporeal hemosorption and enterosorption for eliminating the intoxication. Higher efficacy of tuberculosis treatment in the alcoholic patients was achieved with intravenous drop-wise infusion of antituberculous drugs along with other routes of administration. For increasing the cellular immunity, the patients were treated with chlorophylliptum or T-activin. Continuation of the complex antialcoholic and antituberculous treatment of outpatients along with simultaneous observation by phthisiologists and narcologists provided higher results.

摘要

结果表明,肺结核患者中酒精中毒的患病率较高,且在免疫力低下的情况下两种疾病的进展结果往往不佳,包括长期随访结果。使用专门构建的仪器研究大脑皮层的神经动力学特征以及测定血清中的γ-谷氨酰转肽酶有助于酒精中毒前期病变的诊断。对于结核病患者,采用一氧化二氮和氧气混合的麻醉心理疗法、植入esperal以及应用新制剂rifusal进行酒精中毒治疗,以及应用体外血液吸附和肠吸附来消除中毒,疗效更高。对于酗酒患者,通过静脉滴注抗结核药物以及其他给药途径,结核病治疗的疗效更高。为增强细胞免疫力,患者接受叶绿素iptum或T-激活素治疗。门诊患者继续进行综合戒酒和抗结核治疗,同时由肺病学家和麻醉学家进行同步观察,取得了更好的效果。

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