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[使用化学制剂和T-激活素治疗播散型破坏性肺结核患者的疗效]

[Efficacy of treating patients with disseminated forms of destructive pulmonary tuberculosis using chemical preparations and T-activin].

作者信息

Chukanov V I, Gergert V Ia, Khomenko I S

出版信息

Probl Tuberk. 1989(6):30-3.

PMID:2771908
Abstract

The use of T-activin in combination with chemical drugs allowed to markedly increase efficacy of the treatment. As a result of the treatment significant improvement was found in 17 (41.5 per cent) out of 41 patients with marked disorders in cellular immunity and severe tuberculosis. At the same time in the patients treated with the chemotherapeutics alone the improvement was stated only in 18.5 per cent of the patients. T-Activin improved the indices of cellular immunity and eliminated imbalance in regulatory subpopulations of T-helper and T-suppressor cells.

摘要

将T-激活素与化学药物联合使用可显著提高治疗效果。在41例细胞免疫严重紊乱的重度结核病患者中,17例(41.5%)经治疗后有显著改善。同时,仅接受化疗的患者中,改善的比例仅为18.5%。T-激活素改善了细胞免疫指标,消除了辅助性T细胞和抑制性T细胞调节亚群的失衡。

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