Zhukova E M
Probl Tuberk. 1995(3):25-7.
Tactivin was tried in combined therapy of 49 new-onset cases with destructive pulmonary tuberculosis and gastrointestinal lesions. 52 controls received antibacterial drugs alone. Tactivin increased T-lymphocyte count and improved their subpopulations proportion in a shorter period of time. Immunochemotherapy contributed to efficacy of the main and associated disease treatment. Healing of the destruction foci occurred in 87% versus 70% in controls, side effects of antibacterial drugs and exacerbations of gastrointestinal diseases arose 2-2.5 times less frequently.
对49例新发的伴有胃肠道病变的浸润性肺结核患者采用联合疗法试用了激肽释放酶原。52例对照仅接受抗菌药物治疗。激肽释放酶原能在更短时间内增加T淋巴细胞计数并改善其亚群比例。免疫化疗有助于主病及相关疾病治疗的疗效。对照组破坏灶愈合率为70%，而治疗组为87%，抗菌药物的副作用和胃肠道疾病的加重发生率降低了2至2.5倍。
