埃博拉病毒感染的免疫保护。
Immunology of protection from Ebola virus infection.
机构信息
Office of Vaccines Research and Review, U.S. Food and Drug Administration/Center for Biologics Evaluation and Research, Silver Spring, MD, USA.
Division of Microbial and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
出版信息
Sci Transl Med. 2015 May 6;7(286):286ps11. doi: 10.1126/scitranslmed.aaa8202.
A December 2014 meeting reviewed Ebola virus immunology relevant to vaccine development, including Ebola prevention, immunity, assay standardization, and regulatory considerations. Vaccinated humans appear to achieve immune responses comparable in magnitude with those associated with protection in nonhuman primates, suggesting that immunological data could be used to demonstrate vaccine efficacy.
2014 年 12 月的一次会议审查了与疫苗开发相关的埃博拉病毒免疫学，包括埃博拉预防、免疫、检测标准化和监管考虑因素。接种疫苗的人类似乎能够产生与非人类灵长类动物保护相关的免疫反应相当的免疫反应，这表明免疫数据可用于证明疫苗的功效。
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