Aminiahidashti Hamed, Jamali Seyed Reza, Heidari Gorji Ali Morad
Department of Emergency Medicine, Imam Khomeini Hospital, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Education and Development Center, Mazandaran University of Medical Sciences, Sari, Iran.
Toxicol Int. 2014 Sep-Dec;21(3):322-4. doi: 10.4103/0971-6580.155386.
Human intoxication with abamectin is an uncommon but potentially fatal cause of pesticide poisoning. In this study a 42-year-old man was intoxicated with 3600 mg abamectin orally. On admission patient was fully alert with the smell of the poison from the mouth. Vital signs were normal and conjunctiva was hyperemic. Conservative cares such as gastric lavage was performed and charcoal was administered. After 2.5 hours, the patient gradually developed altered mental status as drowsiness, hypotension, tachycardia and dermal erythema. He was treated with H1 and H2 blockers and vasoactive agents and after 2 days was discharged in good condition. In comparison with organophosphates, abamectin intoxication has less risk in humans. However, consumption of large amounts in human can be fatal. Altered mental status could be considered as the first sign of abamectin intoxication. Normal level of consciousness is the best indicator of improvement of the condition. Conservative treatment is recommended.
人类阿维菌素中毒是农药中毒中一种罕见但可能致命的原因。在本研究中，一名42岁男性口服3600毫克阿维菌素中毒。入院时患者神志清醒，口腔有农药气味。生命体征正常，结膜充血。进行了洗胃等保守治疗并给予活性炭。2.5小时后，患者逐渐出现精神状态改变，如嗜睡、低血压、心动过速和皮肤红斑。给予H1和H2阻滞剂及血管活性药物治疗，2天后康复出院。与有机磷相比，阿维菌素中毒对人类的风险较小。然而，人类大量摄入可能致命。精神状态改变可被视为阿维菌素中毒的首要迹象。意识水平正常是病情好转的最佳指标。建议进行保守治疗。
