Bandyopadhyay Arghya, Bhattacharya Shubham, Maiti Barnali, Bose Koushik
Department of Pathology, Burdwan Medical College, Burdwan, West Bengal, India.
J Lab Physicians. 2015 Jan-Jun;7(1):61-3. doi: 10.4103/0974-2727.151694.
Amyloidosis is a group of disorders characterized by an extracellular deposition of an abnormal amount of proteins in a variety of organs resulting from abnormal folding of protein. It typically presents as disseminated deposits. Tumor like localized presentation of amyloidosis in the absence of systemic amyloidosis is referred to as amyloidoma or amyloid tumor. Amyloidoma is the least common presentation of tissue amyloid deposition. Amyloidoma of soft tissue is again a very rare entity, especially in the neck region. Calcification and minimum giant cell reaction can occur in amyloidoma. However, extensive calcification and exuberant giant cell reaction in amyloidoma of soft tissue neck make it difficult to diagnose. In this report, we discuss such a rare case with its differential diagnoses.
淀粉样变性是一组疾病，其特征是由于蛋白质异常折叠导致在各种器官中细胞外沉积异常量的蛋白质。它通常表现为弥漫性沉积物。在没有全身性淀粉样变性的情况下，淀粉样变性的肿瘤样局限性表现被称为淀粉样瘤或淀粉样肿瘤。淀粉样瘤是组织淀粉样沉积最不常见的表现形式。软组织淀粉样瘤同样是一种非常罕见的实体，尤其是在颈部区域。淀粉样瘤可发生钙化和最小程度的巨细胞反应。然而，软组织颈部淀粉样瘤中的广泛钙化和旺盛的巨细胞反应使其难以诊断。在本报告中，我们讨论了这样一个罕见病例及其鉴别诊断。
