Ordeanu Claudia, Pop Diana Cristina, Badea Radu, Csutak Csaba, Todor Nicolae, Ordeanu Calin, Kerekes Reka, Coza Ovidiu, Nagy Viorica, Achimas-Cadariu Patriciu, Irimie Alexandru
Department of Radiotherapy with High Energies and Brachytherapy, Oncology Institute "Prof. Dr. Ion Chiricuta", Street Republicii, No. 34-36, 400015 City of Cluj-Napoca, Cluj County, Romania.
Adults Clinical Hospital, Medical Clinic No. III, Street Croitorilor, No. 19-21, 400162 City of Cluj-Napoca, Cluj County, Romania ; University of Medicine and Farmacy "Iuliu Hatieganu", Street Louis Pasteur, No. 4, 400349 City of Cluj-Napoca, Cluj County, Romania ; Badea Medica Clinic, Street René Descartes, No. 27, 400486 City of Cluj-Napoca, Cluj County, Romania.
Rep Pract Oncol Radiother. 2015 May-Jun;20(3):223-30. doi: 10.1016/j.rpor.2015.01.003. Epub 2015 Feb 17.
The aim of study was to analyze the accuracy of TRUS (transrectal ultrasound) vs. MRI (magnetic resonance imaging) and clinical gynecological examination estimation in the evaluation of tumor dimensions.
The patients inclusion criterion included primarily pathologically squamous cell carcinoma, but excluded were patients who had not undergone BT (brachytherapy) and treated with palliative intent. We offer two types of treatment for locally advanced cervical cancer: (a) radiochemotherapy followed by surgery and (b) exclusive radiochemotherapy. Imaging tests follow the presence of tumor and tumor size (width and thickness). Each examination was performed by a different physician who had no knowledge of the others' findings. All patients underwent MRI prior to EBRT (external beam radiation therapy) while 18 of them also at the time of the first brachytherapy application. For the analysis we used the r-Pearson correlation coefficient.
In 2013, 26 patients with cervical cancer were included. A total of 44 gynecological examinations were performed, 44 MRIs and 18 TRUSs. For the comparisons prior to EBRT the correlation coefficient between TRUS vs. MRI was r = 0.79 for AP and r = 0.83 for LL, for GYN vs. MRI was r = 0.6 for AP and r = 0.75 for LL. Prior to BT for GYN vs. MRI, r values were 0.60 and 0.63 for AP and LL, respectively; for GYN vs. TRUS, r values were 0.56 and 0.78 for AP and LL, respectively.
A high correlation between the three examinations was obtained. As such, TRUS can be considered a suitable method in the evaluation of tumor dimensions.
本研究旨在分析经直肠超声（TRUS）、磁共振成像（MRI）及临床妇科检查在评估肿瘤大小方面的准确性。
患者纳入标准主要为病理诊断为鳞状细胞癌，排除未接受近距离放疗（BT）及姑息性治疗的患者。对于局部晚期宫颈癌，我们提供两种治疗方式：（a）放化疗后手术；（b）单纯放化疗。影像学检查关注肿瘤的存在及大小（宽度和厚度）。每次检查由不了解其他检查结果的不同医生进行。所有患者在接受外照射放疗（EBRT）前均接受了MRI检查，其中18例患者在首次进行近距离放疗时也接受了MRI检查。分析时我们使用了r - Pearson相关系数。
2013年，纳入26例宫颈癌患者。共进行了44次妇科检查、44次MRI检查和18次TRUS检查。在EBRT前进行比较时，TRUS与MRI在前后径（AP）方向的相关系数r = 0.79，在左右径（LL）方向的相关系数r = 0.83；妇科检查与MRI在AP方向的相关系数r = 0.6，在LL方向的相关系数r = 0.75。在BT前，妇科检查与MRI在AP方向的r值分别为0.60和0.63，在LL方向分别为0.60和0.63；妇科检查与TRUS在AP方向的r值分别为0.56和0.78，在LL方向分别为0.56和0.78。
三种检查之间具有高度相关性。因此，TRUS可被视为评估肿瘤大小的一种合适方法。
