Programa de Pós-Graduação em Saúde e Ambiente, Universidade Federal do Maranhão, 65085-580 São Luís, MA, Brazil.
Departamento de Farmácia, Universidade Federal do Maranhão, 65085-580 São Luís, MA, Brazil.
Evid Based Complement Alternat Med. 2015;2015:490765. doi: 10.1155/2015/490765. Epub 2015 Apr 9.
The mosquito Aedes aegypti L. (Diptera: Culicidae) is the major vector of dengue and chikungunya fever. The lack of effective therapies and vaccines for these diseases highlights the need for alternative strategies to control the spread of virus. Therefore, this study investigated the larvicidal potential of essential oils from common plant species obtained from the Chapada das Mesas National Park, Brazil, against third instar A. aegypti larvae. The chemical composition of these oils was determined by gas chromatography coupled to mass spectrometry. The essential oils of Eugenia piauhiensis Vellaff., Myrcia erythroxylon O. Berg, Psidium myrsinites DC., and Siparuna camporum (Tul.) A. DC. were observed to be mainly composed of sesquiterpene hydrocarbons. The essential oil of Lippia gracilis Schauer was composed of oxygenated monoterpenes. Four of the five tested oils were effective against the A. aegypti larvae, with the lethal concentration (LC50) ranging from 230 to 292 mg/L after 24 h of exposure. Overall, this work demonstrated the possibility of developing larvicidal products against A. aegypti by using essential oils from the flora of the Brazilian Legal Amazon. This in turn demonstrates the potential of using natural resources for the control of disease vectors.
埃及伊蚊（Aedes aegypti L.）（双翅目：蚊科）是登革热和基孔肯雅热的主要传播媒介。由于缺乏针对这些疾病的有效治疗方法和疫苗，因此需要采取替代策略来控制病毒的传播。因此，本研究调查了从巴西 Chapada das Mesas 国家公园获得的常见植物物种的精油对第三龄埃及伊蚊幼虫的杀幼虫潜力。通过气相色谱-质谱联用技术确定了这些油的化学成分。Eugenia piauhiensis Vellaff.、Myrcia erythroxylon O. Berg、Psidium myrsinites DC. 和 Siparuna camporum（Tul.）A. DC 的精油主要由倍半萜烃组成。Lippia gracilis Schauer 的精油由含氧单萜组成。在暴露 24 小时后，五种测试油中的四种对埃及伊蚊幼虫有效，致死浓度（LC50）范围为 230 至 292 mg/L。总的来说，这项工作证明了通过使用巴西亚马逊法定地区植物群的精油来开发针对埃及伊蚊的杀幼虫产品的可能性。这反过来又证明了利用自然资源控制病媒的潜力。
