Santos Eduarda Florencio, Anselmo Wevertton Marllon, de Lemos Eurico Eduardo Pinto, de Aguiar Júlio César Ribeiro de Oliveira Farias, da Silva Ana Carla, Dos Santos Fábio Henrique Galdino, Arruda Camila Caroline Lopes, Aguiar João Vitor Castro, de Andrade José Jorge Almeida, da Rocha Suyana Karolyne Lino, Araújo Liderlânio de Almeida, Pereira Júnior Paulo Gomes, Albuquerque Caroline Francisca de Oliveira, Sousa Edymilaís da Silva, Dos Santos Gerlan Lino, da Conceição Tamires Zuleide, de Andrade Leonardo Arcanjo, Soares Luiz Alberto Lira, Ferreira Magda Rhayanny Assunção, Navarro Daniela Maria do Amaral Ferraz
Department of Chemistry, Center for Exact and Natural Sciences, Federal University of Pernambuco, Recife 50670-901, Brazil.
Engineering and Agricultural Sciences Campus, Federal University of Alagoas, Maceió 57072-900, Brazil.
Molecules. 2025 Jul 25;30(15):3116. doi: 10.3390/molecules30153116.
The mosquito is the vector responsible for the transmission of important arboviruses such as dengue fever, Chikungunya, Zika virus, and yellow fever. These diseases affect millions of people and exert impacts on healthcare systems throughout the world. Given the increasing resistance to synthetic insecticides, essential oils from plants constitute an ecologically viable alternative for the control of this vector. The aim of the present study was to investigate the larvicidal activity of the essential oil (EO), aqueous extract, rutin, and hydrolate from the leaves of against larvae in the initial L4 stage. The yield of EO was 0.47%. Thirty-seven chemical constituents were identified and quantified using chromatographic methods. The major constituents were ()-caryophyllene (27.35%), 1,8-cineole (11.25%), β-selinene (4.92%), and α-muurolene (4.92%). In the larvicidal tests, the lethal concentration (LC) was 201.73 ppm for the essential oil, 15.85% for the aqueous extract, and 22.46 ppm for rutin. The hydrolate had no larvicidal activity. The compounds that exhibited larvicidal activity against constitute a promising option for the development of natural formulations to diminish the propagation of this vector.
蚊子是传播登革热、基孔肯雅热、寨卡病毒和黄热病等重要虫媒病毒的媒介。这些疾病影响着数百万人，并对全球医疗系统产生影响。鉴于对合成杀虫剂的抗药性不断增加，植物精油是控制这种媒介的一种生态可行的替代方法。本研究的目的是调查从[植物名称]叶片中提取的精油（EO）、水提取物、芦丁和水解液对处于L4初期阶段的[蚊子名称]幼虫的杀幼虫活性。精油的产率为0.47%。使用色谱方法鉴定并定量了37种化学成分。主要成分是（）-石竹烯（27.35%）、1,8-桉叶素（11.25%）、β-芹子烯（4.92%）和α-穆罗勒烯（4.92%）。在杀幼虫试验中，精油的致死浓度（LC）为201.73 ppm，水提取物为15.85%，芦丁为22.46 ppm。水解液没有杀幼虫活性。对[蚊子名称]表现出杀幼虫活性的化合物是开发天然制剂以减少这种媒介传播的一个有前景的选择。
