Ponnusamy Arvind, Woywodt Alexander, Reeve Roy, Kondlapudi Jyothi, Lewis David
Renal Department, Salford Royal NHS Foundation Trust, Salford.
Renal Unit , Lancashire Teaching Hospitals NHS Foundation Trust , Preston, Lancashire.
NDT Plus. 2009 Oct;2(5):370-2. doi: 10.1093/ndtplus/sfp090. Epub 2009 Jul 17.
Kikuchi disease (KD) is a rare form of necrotizing lymphadenitis. KD usually presents with cervical lymphadenopathy and fever in young women. It tends to run a benign course and resolve spontaneously within months. The aetiology of the disease is still unclear although a variety of infectious agents have been postulated. There is also a documented but rare association with systemic lupus erythematosus (SLE). We present the case of a young woman with biopsy-proven KD who subsequently developed SLE with biopsy-proven lupus nephritis. Nephrologists should be aware of KD as it may precede the development of SLE and lupus nephritis.
菊池病（KD）是一种罕见的坏死性淋巴结炎。KD通常表现为年轻女性的颈部淋巴结病和发热。它往往呈良性病程，数月内可自发缓解。尽管已推测出多种感染因子，但该病的病因仍不清楚。与系统性红斑狼疮（SLE）也有文献记载但罕见的关联。我们报告一例经活检证实为KD的年轻女性病例，该患者随后发展为经活检证实为狼疮性肾炎的SLE。肾病学家应了解KD，因为它可能先于SLE和狼疮性肾炎的发生。
