作者观点：放射治疗和免疫治疗作为实体瘤的全身治疗方法。
Author's view: radiation and immunotherapy as systemic therapy for solid tumors.
作者信息
Seyedin Steven N, Tang Chad, Welsh James W
机构信息
Department of Radiation Oncology; The University of Texas MD Anderson Cancer Center; Houston, TX USA.
出版信息
Oncoimmunology. 2015 Jan 20;4(3):e986402. doi: 10.4161/2162402X.2014.986402. eCollection 2015 Jan.
Abstract
The ability of tumors to evade detection by the immune system via inducing immunosuppression prompted the therapeutic development of immune checkpoint inhibitors. In our recent review, we discussed findings from preclinical and clinical investigations of these agents utilized in combination with radiation inducing abscopal (systemic) antitumor effects.
摘要
肿瘤通过诱导免疫抑制来逃避免疫系统检测的能力促使了免疫检查点抑制剂的治疗性开发。在我们最近的综述中，我们讨论了这些药物与诱导远隔效应（全身）抗肿瘤作用的放射疗法联合使用的临床前和临床研究结果。
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