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Th2 Cytokines Suppress Lipoteichoic Acid-Induced Matrix Metalloproteinase Expression and Keratinocyte Migration in Response to Wounding.

作者信息

Brauweiler Anne M, Goleva Elena, Hall Clifton F, Leung Donald Y M

机构信息

Department of Pediatrics, National Jewish Health, Denver, Colorado, USA.

Department of Pediatrics, National Jewish Health, Denver, Colorado, USA; Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, USA.

出版信息

J Invest Dermatol. 2015 Oct;135(10):2550-2553. doi: 10.1038/jid.2015.181. Epub 2015 May 7.

DOI:10.1038/jid.2015.181
PMID:25950824
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4567972/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b73/4567972/f641f7eb308a/nihms687602f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b73/4567972/623715c0ae64/nihms687602f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b73/4567972/f641f7eb308a/nihms687602f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b73/4567972/623715c0ae64/nihms687602f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b73/4567972/f641f7eb308a/nihms687602f2.jpg

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本文引用的文献

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Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection.通过激光捕获显微切割技术鉴定特应性皮炎中的新型免疫和屏障基因。
J Allergy Clin Immunol. 2015 Jan;135(1):153-63. doi: 10.1016/j.jaci.2014.10.037.
2
Dupilumab treatment in adults with moderate-to-severe atopic dermatitis.度普利尤单抗治疗中重度特应性皮炎成人患者。
N Engl J Med. 2014 Jul 10;371(2):130-9. doi: 10.1056/NEJMoa1314768.
3
Atopic dermatitis: a disease of altered skin barrier and immune dysregulation.特应性皮炎：一种皮肤屏障改变和免疫失调的疾病。
J Invest Dermatol. 2019 Aug;139(8):1753-1761.e4. doi: 10.1016/j.jid.2019.02.006. Epub 2019 Feb 16.
4
Epithelial barrier repair and prevention of allergy.上皮屏障修复与过敏预防。
J Clin Invest. 2019 Apr 1;129(4):1463-1474. doi: 10.1172/JCI124608. Epub 2019 Feb 18.
5
IL-4 impairs wound healing potential in the skin by repressing fibronectin expression.白细胞介素-4通过抑制纤连蛋白的表达来损害皮肤的伤口愈合潜能。
J Allergy Clin Immunol. 2017 Jan;139(1):142-151.e5. doi: 10.1016/j.jaci.2016.07.012. Epub 2016 Aug 20.
Immunol Rev. 2011 Jul;242(1):233-46. doi: 10.1111/j.1600-065X.2011.01027.x.
4
Infected atopic dermatitis lesions contain pharmacologic amounts of lipoteichoic acid.感染性特应性皮炎病灶含有大量的脂磷壁酸。
J Allergy Clin Immunol. 2010 Jan;125(1):146-52.e1-2. doi: 10.1016/j.jaci.2009.09.052. Epub 2009 Dec 4.
5
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling.Th22 细胞代表了一类独特的人类 T 细胞亚群，参与表皮免疫和重塑。
J Clin Invest. 2009 Dec;119(12):3573-85. doi: 10.1172/JCI40202. Epub 2009 Nov 16.
6
IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3.白细胞介素-4和白细胞介素-13通过信号转导和转录激活因子6（STAT-6）、细胞因子信号抑制因子（SOCS）-1和SOCS-3负向调节肿瘤坏死因子-α和干扰素-γ诱导的β-防御素表达。
J Immunol. 2007 Jul 15;179(2):984-92. doi: 10.4049/jimmunol.179.2.984.
7
Cross-talk between RhoGTPases and stress activated kinases for matrix metalloproteinase-9 induction in response to keratinocytes injury.RhoGTP酶与应激激活激酶之间的相互作用，以响应角质形成细胞损伤诱导基质金属蛋白酶-9
J Invest Dermatol. 2003 Dec;121(6):1291-300. doi: 10.1111/j.1523-1747.2003.12627.x.
8
Ectopic localization of matrix metalloproteinase-9 in chronic cutaneous wounds.基质金属蛋白酶-9在慢性皮肤伤口中的异位定位。
Hum Pathol. 2002 Mar;33(3):355-64. doi: 10.1053/hupa.2002.32221.
9
Matrix metalloproteinase inhibitor BB-3103 unlike the serine proteinase inhibitor aprotinin abrogates epidermal healing of human skin wounds ex vivo.与丝氨酸蛋白酶抑制剂抑肽酶不同，基质金属蛋白酶抑制剂BB - 3103在体外可消除人皮肤伤口的表皮愈合。
J Invest Dermatol. 2002 Jan;118(1):55-64. doi: 10.1046/j.0022-202x.2001.01652.x.
10
Transforming growth factor-beta - and tumor necrosis factor-alpha -mediated induction and proteolytic activation of MMP-9 in human skin.转化生长因子-β和肿瘤坏死因子-α介导的人皮肤中基质金属蛋白酶-9的诱导及蛋白水解激活
J Biol Chem. 2001 Jun 22;276(25):22341-50. doi: 10.1074/jbc.M010839200. Epub 2001 Apr 10.