Olejnik Małgorzata, Szprengier-Juszkiewicz Teresa
a Department of Pharmacology and Toxicology , National Veterinary Research Institute , Pulawy , Poland.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(7):1124-8. doi: 10.1080/19440049.2015.1045558. Epub 2015 May 26.
Decoquinate, a chemical coccidiostat used as a feed additive, can occur in eggs due to cross-contamination of feedstuffs for laying hens. An experiment was designed to assess the transfer of decoquinate to hen eggs and its distribution between egg yolk and egg white. Hens were given the feed containing decoquinate at a cross-contamination level (0.34 mg kg(-1)) and collected eggs were analysed using an LC-MS/MS method. The plateau level was reached on the eighth day of the experiment and averaged 8.91 µg kg(-1), which is far below the maximum level established at 20 µg kg(-1) for whole eggs. Decoquinate was deposited mostly in egg yolks (26.2 µg kg(-1)) and did not deplete completely during 14 days of administration of decoquinate-free feed. The results confirmed that administration of cross-contaminated feed is associated with very low risk of non-compliant residue levels of decoquinate in eggs.
地考喹酯是一种用作饲料添加剂的化学抗球虫药,由于蛋鸡饲料原料的交叉污染,它可能会出现在鸡蛋中。设计了一项实验来评估地考喹酯向鸡蛋中的转移及其在蛋黄和蛋清之间的分布。给母鸡喂食含有交叉污染水平(0.34毫克/千克)地考喹酯的饲料,并使用液相色谱-串联质谱法对收集的鸡蛋进行分析。在实验的第八天达到了平稳水平,平均为8.91微克/千克,这远低于全蛋规定的20微克/千克的最高水平。地考喹酯主要沉积在蛋黄中(26.2微克/千克),并且在喂食不含地考喹酯的饲料14天期间并未完全耗尽。结果证实,喂食交叉污染的饲料与鸡蛋中地考喹酯残留水平不符合规定的风险非常低有关。