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缓释哌甲酯治疗共病社交焦虑障碍和注意缺陷/多动障碍的疗效:2例报告

Extended-release Methylphenidate Treatment and Outcomes in Comorbid Social Anxiety Disorder and Attention-deficit/Hyperactivity Disorder: 2 Case Reports.

作者信息

Koyuncu Ahmet, Çelebi Fahri, Ertekin Erhan, Kahn David A

机构信息

KOYUNCU: Academy Social Phobia Center, Istanbul, Turkey ÇELEBI: Department of Child and Adolescent Psychiatry, Zonguldak Women and Children Hospital, Zonguldak, Turkey ERTEKIN: Department of Psychiatry, Istanbul Medical School, Istanbul University, Istanbul, Turkey KAHN: Columbia University College of Physicians and Surgeons, New York, NY.

出版信息

J Psychiatr Pract. 2015 May;21(3):225-31. doi: 10.1097/PRA.0000000000000070.

DOI:10.1097/PRA.0000000000000070
PMID:25955266
Abstract

Social anxiety disorder is frequently comorbid with attention-deficit/hyperactivity disorder (ADHD). However, treatment recommendations are not clear in the presence of such comorbidity. A few studies in the literature have reported improvement in symptoms of both disorders with treatment specific for ADHD (ie, stimulants and atomoxetine). In this report, we present cases of 2 adults with social anxiety disorder and ADHD who were treated with methylphenidate monotherapy. Both cases responded well in terms of not only their ADHD symptoms but also the social anxiety disorder symptoms. Methylphenidate was well tolerated with no significant side effects. More studies are needed to better establish the potential of ADHD medications to be effective for comorbid social anxiety disorder symptoms.

摘要

社交焦虑障碍常与注意力缺陷多动障碍(ADHD)共病。然而,在这种共病情况下,治疗建议并不明确。文献中的一些研究报告称,使用针对ADHD的特定治疗方法(即兴奋剂和托莫西汀)可改善两种障碍的症状。在本报告中,我们介绍了2例患有社交焦虑障碍和ADHD的成人患者,他们接受了哌甲酯单一疗法治疗。两例患者不仅ADHD症状得到改善,社交焦虑障碍症状也有改善。哌甲酯耐受性良好,无明显副作用。需要更多研究来更好地确定ADHD药物对共病社交焦虑障碍症状有效的可能性。

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引用本文的文献

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Front Psychiatry. 2025 Jun 6;16:1597559. doi: 10.3389/fpsyt.2025.1597559. eCollection 2025.
2
ADHD and Anxiety Disorder Comorbidity in Children and Adults: Diagnostic and Therapeutic Challenges.儿童和成人中的注意力缺陷多动障碍与焦虑症共病:诊断和治疗挑战
Curr Psychiatry Rep. 2022 Feb;24(2):129-140. doi: 10.1007/s11920-022-01324-5. Epub 2022 Jan 25.
3
Comorbidity in social anxiety disorder: diagnostic and therapeutic challenges.
社交焦虑障碍中的共病:诊断与治疗挑战
Drugs Context. 2019 Apr 2;8:212573. doi: 10.7573/dic.212573. eCollection 2019.
4
Weekday-only chronic oral methylphenidate self-administration in male rats: Reversibility of the behavioral and physiological effects.雄性大鼠仅在工作日进行慢性口服甲基苯丙胺自我给药:行为和生理效应的可逆性
Behav Brain Res. 2019 Jan 1;356:189-196. doi: 10.1016/j.bbr.2018.08.014. Epub 2018 Aug 24.
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Extended-release methylphenidate monotherapy in patients with comorbid social anxiety disorder and adult attention-deficit/hyperactivity disorder: retrospective case series.合并社交焦虑障碍和成人注意力缺陷多动障碍患者的缓释哌甲酯单药治疗:回顾性病例系列
Ther Adv Psychopharmacol. 2017 Nov;7(11):241-247. doi: 10.1177/2045125317714193. Epub 2017 Jun 21.