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合并社交焦虑障碍和成人注意力缺陷多动障碍患者的缓释哌甲酯单药治疗:回顾性病例系列

Extended-release methylphenidate monotherapy in patients with comorbid social anxiety disorder and adult attention-deficit/hyperactivity disorder: retrospective case series.

作者信息

Koyuncu Ahmet, Çelebi Fahri, Ertekin Erhan, Kök Burcu Ece, Tükel Raşit

机构信息

Academy Social Phobia Center, Atatürk Mah. İkitelli Cad. No:126 A/ Daire:6 Küçükçekmece, Istanbul, Turkey.

Department of Child and Adolescent Psychiatry, Istanbul Medical School, Istanbul University, Istanbul, Turkey.

出版信息

Ther Adv Psychopharmacol. 2017 Nov;7(11):241-247. doi: 10.1177/2045125317714193. Epub 2017 Jun 21.

DOI:10.1177/2045125317714193
PMID:29090087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5638159/
Abstract

BACKGROUND

The relationship between social anxiety disorder (SAD) and attention-deficit/hyperactivity disorder (ADHD) is a subject which has recently become a topic of interest for research.

METHODS

In this study, 20 patients with comorbid SAD and adult ADHD who were treated with extended-release methylphenidate monotherapy were evaluated retrospectively.

RESULTS

Clinical response for both ADHD and SAD symptoms was observed in 17 of 20 patients. Overall, one patient did not respond to treatment and two patients dropped out of treatment at the beginning due to adverse effects.

CONCLUSION

Extended-release methylphenidate improved both SAD and ADHD symptoms and was generally well tolerated. Further studies are required to investigate the relationship between SAD and ADHD.

摘要

背景

社交焦虑障碍(SAD)与注意力缺陷多动障碍(ADHD)之间的关系是最近成为研究热点的一个课题。

方法

在本研究中,对20例合并SAD和成人ADHD且接受缓释哌甲酯单一疗法治疗的患者进行了回顾性评估。

结果

20例患者中有17例的ADHD和SAD症状均有临床反应。总体而言,1例患者对治疗无反应,2例患者因不良反应在治疗初期退出。

结论

缓释哌甲酯改善了SAD和ADHD症状,且总体耐受性良好。需要进一步研究来探究SAD与ADHD之间的关系。

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本文引用的文献

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J Psychiatr Pract. 2015 May;21(3):225-31. doi: 10.1097/PRA.0000000000000070.
2
Predominantly Inattentive Type of ADHD is Associated With Social Anxiety Disorder.注意缺陷多动障碍的主要注意力不集中型与社交焦虑障碍有关。
J Atten Disord. 2015 Oct;19(10):856-64. doi: 10.1177/1087054714533193. Epub 2014 May 9.
3
Psychiatric Comorbidity at the Time of Diagnosis in Adults With ADHD: The CAT Study.成人注意力缺陷多动障碍(ADHD)诊断时的精神共病:CAT研究
J Atten Disord. 2016 Dec;20(12):1066-1075. doi: 10.1177/1087054713518240. Epub 2014 Jan 24.
4
Methylphenidate treatment in children with attention deficit hyperactivity disorder and comorbid social phobia.哌醋甲酯治疗伴有共患社交恐惧症的注意缺陷多动障碍儿童。
Int Clin Psychopharmacol. 2014 Jul;29(4):212-5. doi: 10.1097/YIC.0000000000000029.
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Psychiatric comorbidity distribution and diversities in children and adolescents with attention deficit/hyperactivity disorder: a study from Turkey.土耳其的一项研究显示,注意缺陷多动障碍患儿和青少年的精神共病分布及多样性。
Neuropsychiatr Dis Treat. 2013;9:1791-9. doi: 10.2147/NDT.S54283. Epub 2013 Nov 14.
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