Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Trends Plant Sci. 2015 Jul;20(7):453-61. doi: 10.1016/j.tplants.2015.04.003. Epub 2015 May 5.
FAR-RED ELONGATED HYPOCOTYLS3 (FHY3) and FAR-RED-IMPAIRED RESPONSE1 (FAR1), initially identified as crucial components of phytochrome A (phyA)-mediated far-red (FR) light signaling in Arabidopsis thaliana, are the founding members of the FAR1-related sequence (FRS) family of transcription factors present in most angiosperms. These proteins share extensive similarity with the Mutator-like transposases, indicative of their evolutionary history of 'molecular domestication'. Here we review emerging multifaceted roles of FHY3/FAR1 in diverse developmental and physiological processes, including UV-B signaling, circadian clock entrainment, flowering, chloroplast biogenesis, chlorophyll biosynthesis, programmed cell death, reactive oxygen species (ROS) homeostasis, abscisic acid (ABA) signaling, and branching. The domestication of FHY3/FAR1 may enable angiosperms to better integrate various endogenous and exogenous signals for coordinated regulation of growth and development, thus enhancing their fitness and adaptation.
远红光延长下胚轴 3（FHY3）和远红光抑制响应 1（FAR1）最初被鉴定为拟南芥中光敏色素 A（phyA）介导的远红光（FR）信号的关键组成部分，是远红光相关序列（FRS）家族转录因子的创始成员，存在于大多数被子植物中。这些蛋白质与 Mutator-like 转座酶具有广泛的相似性，表明它们的进化历史是“分子驯化”。在这里，我们回顾了 FHY3/FAR1 在各种发育和生理过程中的新兴多方面作用，包括 UV-B 信号转导、生物钟节律、开花、叶绿体生物发生、叶绿素生物合成、细胞程序性死亡、活性氧（ROS）稳态、脱落酸（ABA）信号转导和分枝。FHY3/FAR1 的驯化使被子植物能够更好地整合各种内源性和外源性信号，以协调生长和发育的调节，从而提高其适应性和适应性。
